Role of Genetic Variations in the Hepatic Handling of Drugs

Role of Genetic Variations in the Hepatic Handling of Drugs

The liver plays a pivotal role in drug handling due to its contribution to the processes of detoxification (phases 0 to 3). In addition, the liver is also an essential organ for the mechanism of action of many families of drugs, such as cholesterol-lowering, antidiabetic, antiviral, anticoagulant, a...

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Bibliographic Details
Main Authors:	Jose J. G. Marin, Maria A. Serrano, Maria J. Monte, Anabel Sanchez-Martin, Alvaro G. Temprano, Oscar Briz, Marta R. Romero
Format:	Article
Language:	English
Published:	MDPI AG 2020-04-01
Series:	International Journal of Molecular Sciences
Subjects:	detoxification haplotype isoform metabolism mutation pharmacogenomics
Online Access:	https://www.mdpi.com/1422-0067/21/8/2884

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