The metabotropic glutamate 5 receptor modulates extinction and reinstatement of methamphetamine-seeking in mice.

The metabotropic glutamate 5 receptor modulates extinction and reinstatement of methamphetamine-seeking in mice.

Methamphetamine (METH) is a highly addictive psychostimulant with no therapeutics registered to assist addicts in discontinuing use. Glutamatergic dysfunction has been implicated in the development and maintenance of addiction. We sought to assess the involvement of the metabotropic glutamate 5 rece...

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Bibliographic Details
Main Authors: Rose Chesworth, Robyn M Brown, Jee Hyun Kim, Andrew J Lawrence
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3701637?pdf=render

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