Comparative assessment of kidneys’ functional state in patients with acute coronary syndrome
Aim. To determine the severity of chronic kidney disease (CKD) in patients after acute coronary syndrome (ACS).Material and methods. The study was conducted in Semey (Semipalatinsk), East Kazakhstan region. The case histories of patients with ACS who were admitted to the University Hospital of the S...
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2019-04-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/2994 |
| _version_ | 1826561173009465344 |
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| author | N. A. Balashkevich L. B. Dyusenova B. A. Zhetpisbaev M. S. Kazymov I. A. Izbasarova O. A. Borovikova G. M. Shalgumbaeva |
| author_facet | N. A. Balashkevich L. B. Dyusenova B. A. Zhetpisbaev M. S. Kazymov I. A. Izbasarova O. A. Borovikova G. M. Shalgumbaeva |
| author_sort | N. A. Balashkevich |
| collection | DOAJ |
| description | Aim. To determine the severity of chronic kidney disease (CKD) in patients after acute coronary syndrome (ACS).Material and methods. The study was conducted in Semey (Semipalatinsk), East Kazakhstan region. The case histories of patients with ACS who were admitted to the University Hospital of the State Medical University (Semey State Medical University) of the East Kazakhstan Region for 1 year were studied. A total of 659 case histories were analyzed, of which 263 were patients with myocardial infarction (MI), and 396 were patients with unstable angina (UA). The diagnostic criteria for CKD were: proteinuria, levels of creatinine, glomerular filtration rate (GFR) <60 ml/min/1,73 m2. CKD stage was determined by the parameters of GFR.Results. The average proteinuria in patients with MI (Me=0,033) were higher than in patients with UA (Me=0,00), U=39564,5, Z=-5,579 p=0,000. The average values of creatinine in patients with MI were 10,26 mmol/l higher than in patients with UA (t=3,333, df=657, p=0,001). The mean GFR values in patients with MI were lower by 4,69 L/min/1,73 m2 than in patients with UA (t=-3,794, df=657, p=0,000. The highest percentage of CKD in patients with ACS were in stage 2-3, the second stage of CKD was more often diagnosed in patients with UA.Conclusion. The results of study allowed us to characterize the severity of CKD in patients undergoing ACS. We consider that widespread introduction of international and national clinical guidelines on the diagnosis, treatment and prevention of CKD in patients undergoing ACS is needed. |
| first_indexed | 2024-04-09T20:46:29Z |
| format | Article |
| id | doaj.art-5d185c68e57045238078c06448939a0e |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2025-03-14T09:27:58Z |
| publishDate | 2019-04-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-5d185c68e57045238078c06448939a0e2025-03-02T11:42:47Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202019-04-0103485310.15829/1560-4071-2019-3-48-532572Comparative assessment of kidneys’ functional state in patients with acute coronary syndromeN. A. Balashkevich0L. B. Dyusenova1B. A. Zhetpisbaev2M. S. Kazymov3I. A. Izbasarova4O. A. Borovikova5G. M. Shalgumbaeva6State Medical UniversityState Medical UniversityState Medical UniversityState Medical UniversityAstana Medical UniversityOmsk Region Clinical Hospital № 9State Medical UniversityAim. To determine the severity of chronic kidney disease (CKD) in patients after acute coronary syndrome (ACS).Material and methods. The study was conducted in Semey (Semipalatinsk), East Kazakhstan region. The case histories of patients with ACS who were admitted to the University Hospital of the State Medical University (Semey State Medical University) of the East Kazakhstan Region for 1 year were studied. A total of 659 case histories were analyzed, of which 263 were patients with myocardial infarction (MI), and 396 were patients with unstable angina (UA). The diagnostic criteria for CKD were: proteinuria, levels of creatinine, glomerular filtration rate (GFR) <60 ml/min/1,73 m2. CKD stage was determined by the parameters of GFR.Results. The average proteinuria in patients with MI (Me=0,033) were higher than in patients with UA (Me=0,00), U=39564,5, Z=-5,579 p=0,000. The average values of creatinine in patients with MI were 10,26 mmol/l higher than in patients with UA (t=3,333, df=657, p=0,001). The mean GFR values in patients with MI were lower by 4,69 L/min/1,73 m2 than in patients with UA (t=-3,794, df=657, p=0,000. The highest percentage of CKD in patients with ACS were in stage 2-3, the second stage of CKD was more often diagnosed in patients with UA.Conclusion. The results of study allowed us to characterize the severity of CKD in patients undergoing ACS. We consider that widespread introduction of international and national clinical guidelines on the diagnosis, treatment and prevention of CKD in patients undergoing ACS is needed.https://russjcardiol.elpub.ru/jour/article/view/2994acute coronary syndromemyocardial infarctionunstable anginachronic kidney disease |
| spellingShingle | N. A. Balashkevich L. B. Dyusenova B. A. Zhetpisbaev M. S. Kazymov I. A. Izbasarova O. A. Borovikova G. M. Shalgumbaeva Comparative assessment of kidneys’ functional state in patients with acute coronary syndrome Российский кардиологический журнал acute coronary syndrome myocardial infarction unstable angina chronic kidney disease |
| title | Comparative assessment of kidneys’ functional state in patients with acute coronary syndrome |
| title_full | Comparative assessment of kidneys’ functional state in patients with acute coronary syndrome |
| title_fullStr | Comparative assessment of kidneys’ functional state in patients with acute coronary syndrome |
| title_full_unstemmed | Comparative assessment of kidneys’ functional state in patients with acute coronary syndrome |
| title_short | Comparative assessment of kidneys’ functional state in patients with acute coronary syndrome |
| title_sort | comparative assessment of kidneys functional state in patients with acute coronary syndrome |
| topic | acute coronary syndrome myocardial infarction unstable angina chronic kidney disease |
| url | https://russjcardiol.elpub.ru/jour/article/view/2994 |
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