Stage-Specific L-Proline Uptake by Amino Acid Transporter Slc6a19/B<sup>0</sup>AT1 Is Required for Optimal Preimplantation Embryo Development in Mice

Stage-Specific L-Proline Uptake by Amino Acid Transporter Slc6a19/B<sup>0</sup>AT1 Is Required for Optimal Preimplantation Embryo Development in Mice

L-proline (Pro) has previously been shown to support normal development of mouse embryos. Recently we have shown that Pro improves subsequent embryo development when added to fertilisation medium during in vitro fertilisation of mouse oocytes. The mechanisms by which Pro improves embryo development...

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Bibliographic Details
Main Authors: Tamara Treleaven, Matthew Zada, Rajini Nagarajah, Charles G. Bailey, John E. J. Rasko, Michael B. Morris, Margot L. Day
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
proline
amino acid transporter
<i>Slc6a19</i>
B<sup>0</sup>AT1
preimplantation embryo
mouse
Online Access:https://www.mdpi.com/2073-4409/12/1/18

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