Toward the Next Generation of Passive Micromixers: A Novel 3-D Design Approach

Passive micromixers are miniaturized instruments that are used to mix fluids in microfluidic systems. In microchannels, combination of laminar flows and small diffusion constants of mixing liquids produce a difficult mixing environment. In particular, in very low Reynolds number flows, e.g., Re <...

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Main Authors: Mahmut Burak Okuducu, Mustafa M. Aral
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/12/4/372
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author Mahmut Burak Okuducu
Mustafa M. Aral
author_facet Mahmut Burak Okuducu
Mustafa M. Aral
author_sort Mahmut Burak Okuducu
collection DOAJ
description Passive micromixers are miniaturized instruments that are used to mix fluids in microfluidic systems. In microchannels, combination of laminar flows and small diffusion constants of mixing liquids produce a difficult mixing environment. In particular, in very low Reynolds number flows, e.g., Re < 10, diffusive mixing cannot be promoted unless a large interfacial area is formed between the fluids to be mixed. Therefore, the mixing distance increases substantially due to a slow diffusion process that governs fluid mixing. In this article, a novel 3-D passive micromixer design is developed to improve fluid mixing over a short distance. Computational Fluid Dynamics (CFD) simulations are used to investigate the performance of the micromixer numerically. The circular-shaped fluid overlapping (CSFO) micromixer design proposed is examined in several fluid flow, diffusivity, and injection conditions. The outcomes show that the CSFO geometry develops a large interfacial area between the fluid bodies. Thus, fluid mixing is accelerated in vertical and/or horizontal directions depending on the injection type applied. For the smallest molecular diffusion constant tested, the CSFO micromixer design provides more than 90% mixing efficiency in a distance between 260 and 470 µm. The maximum pressure drop in the micromixer is found to be less than 1.4 kPa in the highest flow conditioned examined.
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spelling doaj.art-5d19859b48234961b55fc3938e2213632023-11-21T13:29:41ZengMDPI AGMicromachines2072-666X2021-03-0112437210.3390/mi12040372Toward the Next Generation of Passive Micromixers: A Novel 3-D Design ApproachMahmut Burak Okuducu0Mustafa M. Aral1School of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USADesign and Simulation Technologies Inc., Istanbul 34860, TurkeyPassive micromixers are miniaturized instruments that are used to mix fluids in microfluidic systems. In microchannels, combination of laminar flows and small diffusion constants of mixing liquids produce a difficult mixing environment. In particular, in very low Reynolds number flows, e.g., Re < 10, diffusive mixing cannot be promoted unless a large interfacial area is formed between the fluids to be mixed. Therefore, the mixing distance increases substantially due to a slow diffusion process that governs fluid mixing. In this article, a novel 3-D passive micromixer design is developed to improve fluid mixing over a short distance. Computational Fluid Dynamics (CFD) simulations are used to investigate the performance of the micromixer numerically. The circular-shaped fluid overlapping (CSFO) micromixer design proposed is examined in several fluid flow, diffusivity, and injection conditions. The outcomes show that the CSFO geometry develops a large interfacial area between the fluid bodies. Thus, fluid mixing is accelerated in vertical and/or horizontal directions depending on the injection type applied. For the smallest molecular diffusion constant tested, the CSFO micromixer design provides more than 90% mixing efficiency in a distance between 260 and 470 µm. The maximum pressure drop in the micromixer is found to be less than 1.4 kPa in the highest flow conditioned examined.https://www.mdpi.com/2072-666X/12/4/372micromixerdiffusive mixingpassive mixingfluid overlappingsequential injectionsegmentation
spellingShingle Mahmut Burak Okuducu
Mustafa M. Aral
Toward the Next Generation of Passive Micromixers: A Novel 3-D Design Approach
Micromachines
micromixer
diffusive mixing
passive mixing
fluid overlapping
sequential injection
segmentation
title Toward the Next Generation of Passive Micromixers: A Novel 3-D Design Approach
title_full Toward the Next Generation of Passive Micromixers: A Novel 3-D Design Approach
title_fullStr Toward the Next Generation of Passive Micromixers: A Novel 3-D Design Approach
title_full_unstemmed Toward the Next Generation of Passive Micromixers: A Novel 3-D Design Approach
title_short Toward the Next Generation of Passive Micromixers: A Novel 3-D Design Approach
title_sort toward the next generation of passive micromixers a novel 3 d design approach
topic micromixer
diffusive mixing
passive mixing
fluid overlapping
sequential injection
segmentation
url https://www.mdpi.com/2072-666X/12/4/372
work_keys_str_mv AT mahmutburakokuducu towardthenextgenerationofpassivemicromixersanovel3ddesignapproach
AT mustafamaral towardthenextgenerationofpassivemicromixersanovel3ddesignapproach