Population dynamics of EMT elucidates the timing and distribution of phenotypic intra-tumoral heterogeneity
Summary: The Epithelial-to-Mesenchymal Transition (EMT) is a hallmark of cancer metastasis and morbidity. EMT is a non-binary process, and cells can be stably arrested en route to EMT in an intermediate hybrid state associated with enhanced tumor aggressiveness and worse patient outcomes. Understand...
Main Authors: | Annice Najafi, Mohit K. Jolly, Jason T. George |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-07-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004223010416 |
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