Pain related cortical oscillations: Methodological advances and potential applications
Alongside the time-locked event-related potentials (ERPs), nociceptive somatosensory inputs can induce modulations of ongoing oscillations, appeared as event-related synchronization or desynchronization (ERS/ERD) in different frequency bands. These ERD/ERS activities are suggested to reflect various...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-02-01
|
| Series: | Frontiers in Computational Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncom.2016.00009/full |
| _version_ | 1818790719423250432 |
|---|---|
| author | Weiwei ePeng Dandan eTang |
| author_facet | Weiwei ePeng Dandan eTang |
| author_sort | Weiwei ePeng |
| collection | DOAJ |
| description | Alongside the time-locked event-related potentials (ERPs), nociceptive somatosensory inputs can induce modulations of ongoing oscillations, appeared as event-related synchronization or desynchronization (ERS/ERD) in different frequency bands. These ERD/ERS activities are suggested to reflect various aspects of pain perception, including the representation, encoding, assessment, and integration of the nociceptive sensory inputs, as well as behavioral responses to pain, even the precise details of their roles remain unclear. Previous studies investigating the functional relevance of ERD/ERS activities in pain perception were normally done by assessing their latencies, frequencies, magnitudes, and scalp distributions, which would be then correlated with subjective pain perception or stimulus intensity. Nevertheless, these temporal, spectral, and spatial profiles of stimulus induced ERD/ERS could only partly reveal the dynamics of brain oscillatory activities. Indeed, additional parameters, including but not limited to, phase, neural generator, and cross frequency couplings, should be paid attention to comprehensively and systemically evaluate the dynamics of oscillatory activities associated with pain perception and behavior. This would be crucial in exploring the psychophysiological mechanisms of neural oscillation, and in understanding the neural functions of cortical oscillations involved in pain perception and behavior. Notably, some chronic pain (e.g., neurogenic pain and complex regional pain syndrome) patients are often associated with the occurrence of abnormal synchronized oscillatory brain activities, and selectively modulating cortical oscillatory activities has been showed to be a potential therapy strategy to relieve pain with the application of neurostimulation techniques, e.g., repeated transcranial magnetic stimulation and transcranial alternating current stimulation. Thus, the investigation of the oscillatory activities proceeding from phenomenology to function, opens new perspectives to address questions in human pain psychophysiology and pathophysiology, thereby promoting the establishment of rational therapeutic strategy. |
| first_indexed | 2024-12-18T14:59:56Z |
| format | Article |
| id | doaj.art-5d20494e37f444428fe1b3a492d86afe |
| institution | Directory Open Access Journal |
| issn | 1662-5188 |
| language | English |
| last_indexed | 2024-12-18T14:59:56Z |
| publishDate | 2016-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Computational Neuroscience |
| spelling | doaj.art-5d20494e37f444428fe1b3a492d86afe2022-12-21T21:03:55ZengFrontiers Media S.A.Frontiers in Computational Neuroscience1662-51882016-02-011010.3389/fncom.2016.00009178569Pain related cortical oscillations: Methodological advances and potential applicationsWeiwei ePeng0Dandan eTang1Southwest UniversityZunyi Normal CollegeAlongside the time-locked event-related potentials (ERPs), nociceptive somatosensory inputs can induce modulations of ongoing oscillations, appeared as event-related synchronization or desynchronization (ERS/ERD) in different frequency bands. These ERD/ERS activities are suggested to reflect various aspects of pain perception, including the representation, encoding, assessment, and integration of the nociceptive sensory inputs, as well as behavioral responses to pain, even the precise details of their roles remain unclear. Previous studies investigating the functional relevance of ERD/ERS activities in pain perception were normally done by assessing their latencies, frequencies, magnitudes, and scalp distributions, which would be then correlated with subjective pain perception or stimulus intensity. Nevertheless, these temporal, spectral, and spatial profiles of stimulus induced ERD/ERS could only partly reveal the dynamics of brain oscillatory activities. Indeed, additional parameters, including but not limited to, phase, neural generator, and cross frequency couplings, should be paid attention to comprehensively and systemically evaluate the dynamics of oscillatory activities associated with pain perception and behavior. This would be crucial in exploring the psychophysiological mechanisms of neural oscillation, and in understanding the neural functions of cortical oscillations involved in pain perception and behavior. Notably, some chronic pain (e.g., neurogenic pain and complex regional pain syndrome) patients are often associated with the occurrence of abnormal synchronized oscillatory brain activities, and selectively modulating cortical oscillatory activities has been showed to be a potential therapy strategy to relieve pain with the application of neurostimulation techniques, e.g., repeated transcranial magnetic stimulation and transcranial alternating current stimulation. Thus, the investigation of the oscillatory activities proceeding from phenomenology to function, opens new perspectives to address questions in human pain psychophysiology and pathophysiology, thereby promoting the establishment of rational therapeutic strategy.http://journal.frontiersin.org/Journal/10.3389/fncom.2016.00009/fullPaincortical oscillationsElectroencephalography (EEG)Event-related desynchronization (ERD)Event-related synchronization (ERS) |
| spellingShingle | Weiwei ePeng Dandan eTang Pain related cortical oscillations: Methodological advances and potential applications Frontiers in Computational Neuroscience Pain cortical oscillations Electroencephalography (EEG) Event-related desynchronization (ERD) Event-related synchronization (ERS) |
| title | Pain related cortical oscillations: Methodological advances and potential applications |
| title_full | Pain related cortical oscillations: Methodological advances and potential applications |
| title_fullStr | Pain related cortical oscillations: Methodological advances and potential applications |
| title_full_unstemmed | Pain related cortical oscillations: Methodological advances and potential applications |
| title_short | Pain related cortical oscillations: Methodological advances and potential applications |
| title_sort | pain related cortical oscillations methodological advances and potential applications |
| topic | Pain cortical oscillations Electroencephalography (EEG) Event-related desynchronization (ERD) Event-related synchronization (ERS) |
| url | http://journal.frontiersin.org/Journal/10.3389/fncom.2016.00009/full |
| work_keys_str_mv | AT weiweiepeng painrelatedcorticaloscillationsmethodologicaladvancesandpotentialapplications AT dandanetang painrelatedcorticaloscillationsmethodologicaladvancesandpotentialapplications |