Carbapenem-Only Combination Therapy against Multi-Drug Resistant <i>Pseudomonas aeruginosa</i>: Assessment of In Vitro and In Vivo Efficacy and Mode of Action

Carbapenem-Only Combination Therapy against Multi-Drug Resistant <i>Pseudomonas aeruginosa</i>: Assessment of In Vitro and In Vivo Efficacy and Mode of Action

The aim of the study was to determine the efficacy of carbapenem-only combination treatments derived from four approved drugs (meropenem, doripenem, ertapenem and imipenem) against a MDR strain of <i>P. aeruginosa</i> in a <i>Galleria mellonella</i> larvae infection model. &l...

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Bibliographic Details
Main Authors: Brendan Mackay, Benjamin J. Parcell, Sally L. Shirran, Peter J. Coote
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Antibiotics
Subjects:
antibiotic
resistance
meropenem
doripenem
ertapenem
imipenem
Online Access:https://www.mdpi.com/2079-6382/11/11/1467

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