D-dimer level and Wells score in women undergone Lymphadenectomy in Gynecological Cancer to Assess Risk of Deep Venous Thrombosis
Background: Cancers of the female reproductive system - are an important cause of cancer morbidity and mortality worldwide. A deep-vein thrombosis is a blood clot that forms within the deep veins, usually of the leg. The D-Dimer is a by-product of the blood clotting and break-down process that can...
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| Format: | Article |
| Language: | English |
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College of Medicine University of Baghdad
2022-10-01
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| Series: | مجلة كلية الطب |
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| Online Access: | https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1944 |
| _version_ | 1797369866925113344 |
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| author | nawfal azzo safa daud |
| author_facet | nawfal azzo safa daud |
| author_sort | nawfal azzo |
| collection | DOAJ |
| description |
Background: Cancers of the female reproductive system - are an important cause of cancer morbidity and mortality worldwide. A deep-vein thrombosis is a blood clot that forms within the deep veins, usually of the leg. The D-Dimer is a by-product of the blood clotting and break-down process that can be measured via analysis of a blood sample.
Aim of the study: To predict the risk of deep venous thrombosis by used serum D-dimer and wells score after pelvic lymphadenectomy in gynecological cancer.
Patients and method: a prospective observational cross-sectional study was carried out in the Department of Obstetrics and Gynecology/ Baghdad Teaching Hospital, from 1 January 2021 to 30 Dec. 2021. A total number of 45 (22 endometrial cancer, 12 ovarian, 11 cervical cancer).
Results: the mean level of pre-operative D-dimer in endometrial cancer was (423.2± 123.9) while in post-operative was (987±125.1), the mean level of pre-operative D-dimer in ovarian cancer was (602±320.7) while in post-operative was (901.5± 412), mean level of pre-operative D-dimer in cervical cancer was (339±157) while in postoperative was (1214±327), and the mean level of pre-operative D-dimer in all gynecological cancer was (541±167) while in post-operative was (1016±302). The mean of wells score of those who are likely to developed DVT(n=7)in pre-op. was(2.3±0.02)while for those who unlikely to develop DVT(38)was(2.03±0.4)with statistically significant difference(p=0.04)while highly significant difference found in pre and post operatively between the group of DVT(p˂0.001).
Conclusion: Highly significant increase of post-operative D-dimer in all gynecological cancer patients.
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| first_indexed | 2024-03-08T17:53:12Z |
| format | Article |
| id | doaj.art-5d23445c027c43028fa198091901e88c |
| institution | Directory Open Access Journal |
| issn | 0041-9419 2410-8057 |
| language | English |
| last_indexed | 2024-03-08T17:53:12Z |
| publishDate | 2022-10-01 |
| publisher | College of Medicine University of Baghdad |
| record_format | Article |
| series | مجلة كلية الطب |
| spelling | doaj.art-5d23445c027c43028fa198091901e88c2024-01-02T06:23:44ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572022-10-01643D-dimer level and Wells score in women undergone Lymphadenectomy in Gynecological Cancer to Assess Risk of Deep Venous Thrombosisnawfal azzosafa daud Background: Cancers of the female reproductive system - are an important cause of cancer morbidity and mortality worldwide. A deep-vein thrombosis is a blood clot that forms within the deep veins, usually of the leg. The D-Dimer is a by-product of the blood clotting and break-down process that can be measured via analysis of a blood sample. Aim of the study: To predict the risk of deep venous thrombosis by used serum D-dimer and wells score after pelvic lymphadenectomy in gynecological cancer. Patients and method: a prospective observational cross-sectional study was carried out in the Department of Obstetrics and Gynecology/ Baghdad Teaching Hospital, from 1 January 2021 to 30 Dec. 2021. A total number of 45 (22 endometrial cancer, 12 ovarian, 11 cervical cancer). Results: the mean level of pre-operative D-dimer in endometrial cancer was (423.2± 123.9) while in post-operative was (987±125.1), the mean level of pre-operative D-dimer in ovarian cancer was (602±320.7) while in post-operative was (901.5± 412), mean level of pre-operative D-dimer in cervical cancer was (339±157) while in postoperative was (1214±327), and the mean level of pre-operative D-dimer in all gynecological cancer was (541±167) while in post-operative was (1016±302). The mean of wells score of those who are likely to developed DVT(n=7)in pre-op. was(2.3±0.02)while for those who unlikely to develop DVT(38)was(2.03±0.4)with statistically significant difference(p=0.04)while highly significant difference found in pre and post operatively between the group of DVT(p˂0.001). Conclusion: Highly significant increase of post-operative D-dimer in all gynecological cancer patients. https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1944DVT, gynecologic cancer, wells score, D-dimer, Lymphadenectomy |
| spellingShingle | nawfal azzo safa daud D-dimer level and Wells score in women undergone Lymphadenectomy in Gynecological Cancer to Assess Risk of Deep Venous Thrombosis مجلة كلية الطب DVT, gynecologic cancer, wells score, D-dimer, Lymphadenectomy |
| title | D-dimer level and Wells score in women undergone Lymphadenectomy in Gynecological Cancer to Assess Risk of Deep Venous Thrombosis |
| title_full | D-dimer level and Wells score in women undergone Lymphadenectomy in Gynecological Cancer to Assess Risk of Deep Venous Thrombosis |
| title_fullStr | D-dimer level and Wells score in women undergone Lymphadenectomy in Gynecological Cancer to Assess Risk of Deep Venous Thrombosis |
| title_full_unstemmed | D-dimer level and Wells score in women undergone Lymphadenectomy in Gynecological Cancer to Assess Risk of Deep Venous Thrombosis |
| title_short | D-dimer level and Wells score in women undergone Lymphadenectomy in Gynecological Cancer to Assess Risk of Deep Venous Thrombosis |
| title_sort | d dimer level and wells score in women undergone lymphadenectomy in gynecological cancer to assess risk of deep venous thrombosis |
| topic | DVT, gynecologic cancer, wells score, D-dimer, Lymphadenectomy |
| url | https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1944 |
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