Pengaruh Program Pengendalian Resistensi Antimikroba terhadap Penggunaan Antibiotik Profilaksis pada Bedah Obstetri dan Ginekologi
The incidence of surgical site infections (SSI) in obstetric and gynecological surgery is quite high. Rational prophylactic antibiotics in surgery are important strategies for the prevention of SSI. Antimicrobial Stewardship Program (ASP) for rational prophylactic antibiotic use has been carried out...
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| Format: | Article |
| Language: | Indonesian |
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Universitas Gadjah Mada
2020-06-01
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| Series: | Jurnal Manajemen dan Pelayanan Farmasi |
| Subjects: | |
| Online Access: | https://jurnal.ugm.ac.id/jmpf/article/view/53563 |
| _version_ | 1818321199107670016 |
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| author | Winarni Winarni Nanang Munif Yasin Tri Murti Andayani |
| author_facet | Winarni Winarni Nanang Munif Yasin Tri Murti Andayani |
| author_sort | Winarni Winarni |
| collection | DOAJ |
| description | The incidence of surgical site infections (SSI) in obstetric and gynecological surgery is quite high. Rational prophylactic antibiotics in surgery are important strategies for the prevention of SSI. Antimicrobial Stewardship Program (ASP) for rational prophylactic antibiotic use has been carried out. This study aims to determine the rationality of the use of prophylactic antibiotics and incidence rate of SSI, the effect of ASP on the rationality of prophylactic antibiotics and clinical outcomes in obstetric and gynecology surgery. This study used a quasi-experimental pretest postest design without control group with retrospective data collection. Research time for 2 months from May to June 2019. The subjects of this study were obstetric and gynecology surgery patients at Pandan Arang Hospital Boyolali in 2018 who were divided into 2 groups: patients before the ASP and patients after the ASP with a total sample of 93 patients each group. An evaluation of the type, dose, time of administration, route of administration, and duration of prophylactic antibiotics were performed against the standard. Data analysis used the Pearson Chi-square test to see the relationship between rationality and clinical outcomes with ASP. The rationality of prophylactic antibiotic use increased from 0 (0%) cases before the ASP to 52 cases (55.9%) after the ASP. The SSI incidence rate before ASP was 9.7%, down to 4.3% after ASP. There was a significant relationship between the rationality of prophylactic antibiotics and ASP (p <0.05) but the relationship between clinical outcome (SSI incidence) and ASP was not significant (p> 0.05). The result of this study can be used to promote the implementation of ASP in other wards to increase rational use of antibiotics. |
| first_indexed | 2024-12-13T10:37:06Z |
| format | Article |
| id | doaj.art-5d24fa693a564b039680d8d7398f3257 |
| institution | Directory Open Access Journal |
| issn | 2088-8139 2443-2946 |
| language | Indonesian |
| last_indexed | 2024-12-13T10:37:06Z |
| publishDate | 2020-06-01 |
| publisher | Universitas Gadjah Mada |
| record_format | Article |
| series | Jurnal Manajemen dan Pelayanan Farmasi |
| spelling | doaj.art-5d24fa693a564b039680d8d7398f32572022-12-21T23:50:41ZindUniversitas Gadjah MadaJurnal Manajemen dan Pelayanan Farmasi2088-81392443-29462020-06-0110214515510.22146/jmpf.5356327169Pengaruh Program Pengendalian Resistensi Antimikroba terhadap Penggunaan Antibiotik Profilaksis pada Bedah Obstetri dan GinekologiWinarni Winarni0Nanang Munif Yasin1Tri Murti Andayani2Graduate Program of Clinical Pharmacy, Faculty of Pharmacy, Universitas Gadjah MadaDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Gadjah MadaDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Gadjah MadaThe incidence of surgical site infections (SSI) in obstetric and gynecological surgery is quite high. Rational prophylactic antibiotics in surgery are important strategies for the prevention of SSI. Antimicrobial Stewardship Program (ASP) for rational prophylactic antibiotic use has been carried out. This study aims to determine the rationality of the use of prophylactic antibiotics and incidence rate of SSI, the effect of ASP on the rationality of prophylactic antibiotics and clinical outcomes in obstetric and gynecology surgery. This study used a quasi-experimental pretest postest design without control group with retrospective data collection. Research time for 2 months from May to June 2019. The subjects of this study were obstetric and gynecology surgery patients at Pandan Arang Hospital Boyolali in 2018 who were divided into 2 groups: patients before the ASP and patients after the ASP with a total sample of 93 patients each group. An evaluation of the type, dose, time of administration, route of administration, and duration of prophylactic antibiotics were performed against the standard. Data analysis used the Pearson Chi-square test to see the relationship between rationality and clinical outcomes with ASP. The rationality of prophylactic antibiotic use increased from 0 (0%) cases before the ASP to 52 cases (55.9%) after the ASP. The SSI incidence rate before ASP was 9.7%, down to 4.3% after ASP. There was a significant relationship between the rationality of prophylactic antibiotics and ASP (p <0.05) but the relationship between clinical outcome (SSI incidence) and ASP was not significant (p> 0.05). The result of this study can be used to promote the implementation of ASP in other wards to increase rational use of antibiotics.https://jurnal.ugm.ac.id/jmpf/article/view/53563aspantibiotic prophylaxissurgical site infections |
| spellingShingle | Winarni Winarni Nanang Munif Yasin Tri Murti Andayani Pengaruh Program Pengendalian Resistensi Antimikroba terhadap Penggunaan Antibiotik Profilaksis pada Bedah Obstetri dan Ginekologi Jurnal Manajemen dan Pelayanan Farmasi asp antibiotic prophylaxis surgical site infections |
| title | Pengaruh Program Pengendalian Resistensi Antimikroba terhadap Penggunaan Antibiotik Profilaksis pada Bedah Obstetri dan Ginekologi |
| title_full | Pengaruh Program Pengendalian Resistensi Antimikroba terhadap Penggunaan Antibiotik Profilaksis pada Bedah Obstetri dan Ginekologi |
| title_fullStr | Pengaruh Program Pengendalian Resistensi Antimikroba terhadap Penggunaan Antibiotik Profilaksis pada Bedah Obstetri dan Ginekologi |
| title_full_unstemmed | Pengaruh Program Pengendalian Resistensi Antimikroba terhadap Penggunaan Antibiotik Profilaksis pada Bedah Obstetri dan Ginekologi |
| title_short | Pengaruh Program Pengendalian Resistensi Antimikroba terhadap Penggunaan Antibiotik Profilaksis pada Bedah Obstetri dan Ginekologi |
| title_sort | pengaruh program pengendalian resistensi antimikroba terhadap penggunaan antibiotik profilaksis pada bedah obstetri dan ginekologi |
| topic | asp antibiotic prophylaxis surgical site infections |
| url | https://jurnal.ugm.ac.id/jmpf/article/view/53563 |
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