The Potential Role and Regulatory Mechanisms of MUC5AC in Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is associated with high morbidity and mortality globally. Studies show that airway mucus hypersecretion strongly compromises lung function, leading to frequent hospitalization and mortality, highlighting an urgent need for effective COPD treatments. MUC5A...
Main Authors: | Jingyuan Li, Zuguang Ye |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-09-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/19/4437 |
Similar Items
-
Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma
by: Tomoko Tajiri, et al.
Published: (2022-04-01) -
Inhibition of TRPA1, Endoplasmic Reticulum Stress, Human Airway Epithelial Cell Damage, and Ectopic <i>MUC5AC</i> Expression by Vasaka (<i>Adhatoda vasica</i>; Malabar Nut) Tea
by: Tosifa A. Memon, et al.
Published: (2023-06-01) -
Effect of MUC8 on Airway Inflammation: A Friend or a Foe?
by: Hee-Jae Cha, et al.
Published: (2018-02-01) -
Lactiplantibacillusplantarum APsulloc331261 (GTB1™) promotes butyrate production to suppress mucin hypersecretion in a murine allergic airway inflammation model
by: Hye-Shin Kim, et al.
Published: (2024-02-01) -
Secretoneurin Induces Airway Mucus Hypersecretion by Enhancing the Binding of EGF to NRP1
by: Rui Xu, et al.
Published: (2014-02-01)