Cannabinoids and Reproduction: A Lasting and Intriguing History
Starting from an historical overview of lasting Cannabis use over the centuries, we will focus on a description of the cannabinergic system, with a comprehensive analysis of chemical and pharmacological properties of endogenous and synthetic cannabimimetic analogues. The metabolic pathways and the s...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2010-10-01
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| Series: | Pharmaceuticals |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1424-8247/3/10/3275/ |
| _version_ | 1818807578096828416 |
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| author | Gilda Cobellis Silvia Fasano Riccardo Pierantoni Vincenza Ciaramella Teresa Chioccarelli Giovanna Cacciola Rosanna Chianese Rosaria Meccariello |
| author_facet | Gilda Cobellis Silvia Fasano Riccardo Pierantoni Vincenza Ciaramella Teresa Chioccarelli Giovanna Cacciola Rosanna Chianese Rosaria Meccariello |
| author_sort | Gilda Cobellis |
| collection | DOAJ |
| description | Starting from an historical overview of lasting Cannabis use over the centuries, we will focus on a description of the cannabinergic system, with a comprehensive analysis of chemical and pharmacological properties of endogenous and synthetic cannabimimetic analogues. The metabolic pathways and the signal transduction mechanisms, activated by cannabinoid receptors stimulation, will also be discussed. In particular, we will point out the action of cannabinoids and endocannabinoids on the different neuronal networks involved in reproductive axis, and locally, on male and female reproductive tracts, by emphasizing the pivotal role played by this system in the control of fertility. |
| first_indexed | 2024-12-18T19:27:53Z |
| format | Article |
| id | doaj.art-5d26f6e2d5434f6098f21844106a303f |
| institution | Directory Open Access Journal |
| issn | 1424-8247 |
| language | English |
| last_indexed | 2024-12-18T19:27:53Z |
| publishDate | 2010-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceuticals |
| spelling | doaj.art-5d26f6e2d5434f6098f21844106a303f2022-12-21T20:55:49ZengMDPI AGPharmaceuticals1424-82472010-10-013103275332310.3390/ph3103275Cannabinoids and Reproduction: A Lasting and Intriguing HistoryGilda CobellisSilvia FasanoRiccardo PierantoniVincenza CiaramellaTeresa ChioccarelliGiovanna CacciolaRosanna ChianeseRosaria MeccarielloStarting from an historical overview of lasting Cannabis use over the centuries, we will focus on a description of the cannabinergic system, with a comprehensive analysis of chemical and pharmacological properties of endogenous and synthetic cannabimimetic analogues. The metabolic pathways and the signal transduction mechanisms, activated by cannabinoid receptors stimulation, will also be discussed. In particular, we will point out the action of cannabinoids and endocannabinoids on the different neuronal networks involved in reproductive axis, and locally, on male and female reproductive tracts, by emphasizing the pivotal role played by this system in the control of fertility.http://www.mdpi.com/1424-8247/3/10/3275/cannabinergic system, male reproduction, female reproduction, hypothalamus-pituitary-gonads axis. |
| spellingShingle | Gilda Cobellis Silvia Fasano Riccardo Pierantoni Vincenza Ciaramella Teresa Chioccarelli Giovanna Cacciola Rosanna Chianese Rosaria Meccariello Cannabinoids and Reproduction: A Lasting and Intriguing History Pharmaceuticals cannabinergic system, male reproduction, female reproduction, hypothalamus-pituitary-gonads axis. |
| title | Cannabinoids and Reproduction: A Lasting and Intriguing History |
| title_full | Cannabinoids and Reproduction: A Lasting and Intriguing History |
| title_fullStr | Cannabinoids and Reproduction: A Lasting and Intriguing History |
| title_full_unstemmed | Cannabinoids and Reproduction: A Lasting and Intriguing History |
| title_short | Cannabinoids and Reproduction: A Lasting and Intriguing History |
| title_sort | cannabinoids and reproduction a lasting and intriguing history |
| topic | cannabinergic system, male reproduction, female reproduction, hypothalamus-pituitary-gonads axis. |
| url | http://www.mdpi.com/1424-8247/3/10/3275/ |
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