SMAD2/3 signaling regulates initiation of mouse Wolffian ducts and proximal differentiation in Müllerian ducts

SMAD2/3 signaling regulates initiation of mouse Wolffian ducts and proximal differentiation in Müllerian ducts

Male and female reproductive tracts develop from anterior intermediate mesoderm with similar differentiation processes. The anterior intermediate mesoderm develops into the mesonephros, and the Wolffian duct initiates by epithelialization in the mesonephros. The Müllerian duct invaginates from the c...

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Bibliographic Details
Main Authors: Tadaaki Nakajima, Akihiro Imai, Chihiro Ishii, Kota Tsuruyama, Risa Yamanaka, Yasuhiro Tomooka, Shinta Saito, Noritaka Adachi, Satomi Kohno, Tomomi Sato
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:FEBS Open Bio
Subjects:
epithelialization
fate determination
Müllerian duct
TGFβ signaling
Wolffian duct
Online Access:https://doi.org/10.1002/2211-5463.13729

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