An advanced in vitro human mucosal immune model to predict food sensitizing allergenicity risk: A proof of concept using ovalbumin as model allergen

An advanced in vitro human mucosal immune model to predict food sensitizing allergenicity risk: A proof of concept using ovalbumin as model allergen

BackgroundThe global demand of sustainable food sources leads to introduction of novel foods on the market, which may pose a risk of inducing allergic sensitization. Currently there are no validated in vitro assays mimicking the human mucosal immune system to study sensitizing allergenicity risk of...

Full description

Bibliographic Details
Main Authors:	Marit Zuurveld, Cristina Bueno Díaz, Frank Redegeld, Gert Folkerts, Johan Garssen, Belinda van’t Land, Linette E.M. Willemsen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Series:	Frontiers in Immunology
Subjects:	advanced in vitro model allergic sensitization food allergy mucosal immunity allergenicity risk assessment ovalbumin
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1073034/full

Similar Items

Ovalbumin-Induced Epithelial Activation Directs Monocyte-Derived Dendritic Cells to Instruct Type 2 Inflammation in T Cells Which Is Differentially Modulated by 2′-Fucosyllactose and 3-Fucosyllactose
by: Marit Zuurveld, et al.
Published: (2022-10-01)

Butyrate interacts with the effects of 2’FL and 3FL to modulate in vitro ovalbumin-induced immune activation, and 2’FL lowers mucosal mast cell activation in a preclinical model for hen’s egg allergy
by: M. Zuurveld, et al.
Published: (2023-12-01)

Specific Human Milk Oligosaccharides Differentially Promote Th1 and Regulatory Responses in a CpG-Activated Epithelial/Immune Cell Coculture
by: Marit Zuurveld, et al.
Published: (2023-01-01)

Epithelial-derived galectin-9 containing exosomes contribute to the immunomodulatory effects promoted by 2’-fucosyllactose and short-chain galacto- and long-chain fructo-oligosaccharides
by: Veronica Ayechu-Muruzabal, et al.
Published: (2022-12-01)

Dissecting Airborne Allergens
by: Javier Torres-Borrego, et al.
Published: (2023-09-01)

Differences in grass pollen allergen exposure across Australia
by: Paul J. Beggs, et al.
Published: (2015-02-01)

ALLERGEN-SPECIFIC IMMUNOTHERAPY: VACCINES FOR ALLERGIC DISEASES
by: A. S. Fedorov, et al.
Published: (2015-10-01)

Induction of experimental allergic asthma in cat
by: A.A Bahaodini, et al.
Published: (1997-03-01)

Evaluation of the effectiveness of subcutaneous pollen weed polen allergens
by: L. Yu. Barycheva, et al.
Published: (2023-07-01)

Advocacy of Precision Allergy Molecular Diagnosis in Decision Making for the Eligibility of Customized Allergen Immunotherapy
by: Ruperto González-Pérez, et al.
Published: (2023-12-01)

Common allergens in patients of allergic rhinitis in Gandaki province of Nepal
by: Rajendra Nepali, et al.
Published: (2022-07-01)

Tilianin alleviates airway inflammation in ovalbumin-induced allergic asthma in mice through the regulation of Th2 cytokines and TGF-β1/Smad markers
by: Liyuan Zhang, et al.
Published: (2022-08-01)

Reproxalap Improves Signs and Symptoms of Allergic Conjunctivitis in an Allergen Chamber: A Real-World Model of Allergen Exposure
by: Clark D, et al.
Published: (2022-01-01)

PREVALENCE OF SENSITIZATION TO AIRBORNE ALLERGENS IN PATIENTS WITH ALLERGIC RHINITIS AND ASTHMA IN UKRAINE
by: O.V. Mozyrskaya
Published: (2023-03-01)

Allergens and allergen immunotherapy : subcutaneous, sublingual, and oral /
by: Lockey, Richard F., editor, et al.
Published: (2014)

Modulation of the Epithelial-Immune Cell Crosstalk and Related Galectin Secretion by DP3-5 Galacto-Oligosaccharides and β-3′Galactosyllactose
by: Veronica Ayechu-Muruzabal, et al.
Published: (2022-02-01)

Research progress on clinical application of allergen immunotherapy in children
by: Zhang Pingping, Yang Lifen, Liang Ying, Li Yating
Published: (2022-02-01)

Intradermal Allergen Immunotherapy for Allergic Rhinitis: Current Evidence
by: Kawita Atipas, et al.
Published: (2022-08-01)

Long-term benefit after allergen immunotherapy to HDM in elderly patients with allergic rhinitis
by: Andrzej Bożek, et al.
Published: (2023-07-01)

Characteristics of contact allergens in patients with allergic skin diseases: based on 883 patch tests
by: Linyan YE, et al.
Published: (2022-06-01)

Validation of the method for determining the egg albumin allergen in food products by enzyme-linked immunosorbent assay
by: T. V. Marchenko, et al.
Published: (2023-06-01)

Omalizumab added to allergen immunotherapy increased the effect of therapy in patients with severe local allergic rhinitis
by: Andrzej Bozek, et al.
Published: (2022-11-01)

Correlation between interleukin 4 (IL-4) expression and allergen sensitization in allergic rhinitis patients
by: Asti Widuri
Published: (2021-08-01)

Dynamics of the cellular composition of lymphoid nodules in the lungs of guinea pigs sensitized with ovalbumin
by: S.S. Popko
Published: (2022-09-01)

Identification of peptides sequence and conformation contributed to potential allergenicity of main allergens in yogurts
by: Meijia Huang, et al.
Published: (2023-01-01)

Advances in Allergen Recognition of Bee Pollen and the Potential Application in Allergen Degradation by Microbial Fermentation
by: Shuting YIN, et al.
Published: (2022-07-01)

Study of Skin Sensitivity to Various Allergens by Prick Skin Test in Patients with Bronchial Asthma
by: Adnan Hasan Alwan, et al.
Published: (2019-11-01)

Study of Skin Sensitivity to Various Allergens by Prick Skin Test in Patients with Bronchial Asthma
by: Adnan Hasan Alwan, et al.
Published: (2019-11-01)

A Food Matrix Triggers a Similar Allergic Immune Response in BALB/c Mice Sensitized with Native, Denatured, and Digested Ovalbumin
by: Jesús Gilberto Arámburo-Gálvez, et al.
Published: (2023-08-01)

Salvinorin A inhibits ovalbumin‐stimulated allergic rhinitis and RBL‐2H3 cells degranulation
by: Qiyang Shou, et al.
Published: (2021-08-01)

Molecular Mapping of Allergen Exposome among Different Atopic Phenotypes
by: Ruperto González-Pérez, et al.
Published: (2023-06-01)

Allergenic Activity of Individual Cat Allergen Molecules
by: Daria Trifonova, et al.
Published: (2023-11-01)

Allergen immunotherapy in China
by: Yaqi Yang, et al.
Published: (2024-01-01)

High mobility group box 1 inhibition by BoxA attenuates ovalbumin-induced allergic rhinitis in mice
by: Liyan Yue, et al.
Published: (2022-02-01)

MORPHOLOGICAL CHANGES IN ALVEOLAR MACROPHAGES OF GUINEA PIGS IN THE EARLY AND LATE STAGES OF EXPERIMENTAL OVALBUMIN-INDUCED ALLERGIC INFLAMMATION
by: Popko S. S., et al.
Published: (2022-03-01)

The holo beta‐lactoglobulin lozenge reduces symptoms in cat allergy—Evaluation in an allergen exposure chamber and by titrated nasal allergen challenge
by: Karl‐Christian Bergmann, et al.
Published: (2023-07-01)

Co-Application with Tannic Acid Prevents Transdermal Sensitization to Ovalbumin in Mice
by: Eri Izumi, et al.
Published: (2022-04-01)

Prevalence and Pattern of Inhalant Allergens among Allergic Rhinitis Patients in Vellore – A Cross Sectional Study
by: krithiga Sivakumar, et al.
Published: (2023-03-01)

Prevalence and Pattern of Inhalant Allergens among Allergic Rhinitis Patients in Vellore – A Cross Sectional Study
by: krithiga Sivakumar, et al.
Published: (2023-03-01)

Exposure of Intestinal Epithelial Cells to 2′-Fucosyllactose and CpG Enhances Galectin Release and Instructs Dendritic Cells to Drive Th1 and Regulatory-Type Immune Development
by: Veronica Ayechu-Muruzabal, et al.
Published: (2020-05-01)