Updated clinical practice treat-to-target guidelines for JIA management: the Egyptian College of Pediatric Rheumatology initiative

Abstract Background These updated guidelines aimed to provide appropriate and convenient guidelines for the treatment of various types of juvenile idiopathic arthritis (JIA). Using the Delphi technique, this study was conducted to reach expert consensus on a treat-to-target management strategy for J...

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Main Authors: Y. El Miedany, S. Salah, H. Lotfy, M. El Gaafary, H. Abdulhady, H. Salah, S. I. Nasef, E. Abd El-Latif, Y. Farag, M. Eissa, S. Esam Maher, A. Radwan, Amira T. El-Shanawany, B. M. Medhat, D. El Mikkawy, D. M. Mosa, G. El Deriny, M. Mortada, N. S. Osman, N. A. Fouad, N. E. Elkaraly, S. S. Mohamed, S. A. Tabra, W. A. Hassan, Y. Amer, M. H. Abu-Zaid
Format: Article
Language:English
Published: SpringerOpen 2022-05-01
Series:Egyptian Rheumatology and Rehabilitation
Subjects:
Online Access:https://doi.org/10.1186/s43166-022-00125-1
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author Y. El Miedany
S. Salah
H. Lotfy
M. El Gaafary
H. Abdulhady
H. Salah
S. I. Nasef
E. Abd El-Latif
Y. Farag
M. Eissa
S. Esam Maher
A. Radwan
Amira T. El-Shanawany
B. M. Medhat
D. El Mikkawy
D. M. Mosa
G. El Deriny
M. Mortada
N. S. Osman
N. A. Fouad
N. E. Elkaraly
S. S. Mohamed
S. A. Tabra
W. A. Hassan
Y. Amer
M. H. Abu-Zaid
author_facet Y. El Miedany
S. Salah
H. Lotfy
M. El Gaafary
H. Abdulhady
H. Salah
S. I. Nasef
E. Abd El-Latif
Y. Farag
M. Eissa
S. Esam Maher
A. Radwan
Amira T. El-Shanawany
B. M. Medhat
D. El Mikkawy
D. M. Mosa
G. El Deriny
M. Mortada
N. S. Osman
N. A. Fouad
N. E. Elkaraly
S. S. Mohamed
S. A. Tabra
W. A. Hassan
Y. Amer
M. H. Abu-Zaid
author_sort Y. El Miedany
collection DOAJ
description Abstract Background These updated guidelines aimed to provide appropriate and convenient guidelines for the treatment of various types of juvenile idiopathic arthritis (JIA). Using the Delphi technique, this study was conducted to reach expert consensus on a treat-to-target management strategy for JIA. According to the PICO (patient/population, intervention, comparison, and outcomes) approach, the preliminary scientific committee identified a total of 17 key clinical questions. To assemble evidence on the advantages and dangers associated with JIA treatments, an evidence-based, systematic literature review was conducted. Researchers and clinicians with experience in JIA management were identified by the core leadership team. To establish a consensus on the management suggestions for JIA patients, a Delphi approach (2 rounds) was used. Results An online survey was applied to the expert panel (n = 27), and 26 of them completed both rounds. At the conclusion of round 2, a total of eighteen (18) recommendation items were gathered, which were divided into four sections to address the four key JIA categories. The percentage of those who agreed with the recommendations (ranks 7–9) ranged from 83.2 to 100% (average 86.8%). The phrasing of all 18 clinical standards identified by the scientific committee was agreed upon (i.e. 75% of respondents strongly agreed or agreed). Algorithms have been proposed for the management of JIA polyarthritis, oligoarthritis, and systemic JIA. Conclusion A wide and representative panel of experts initiated a consensus about the management of JIA. The created guidelines give a complete approach to the management of JIA for all healthcare professionals involved in its management, as well as a means of monitoring and evaluating these guidelines on a regular basis.
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spelling doaj.art-5d397636437f46299a767d52545204472022-12-22T03:34:08ZengSpringerOpenEgyptian Rheumatology and Rehabilitation1110-161X2090-32352022-05-0149112510.1186/s43166-022-00125-1Updated clinical practice treat-to-target guidelines for JIA management: the Egyptian College of Pediatric Rheumatology initiativeY. El Miedany0S. Salah1H. Lotfy2M. El Gaafary3H. Abdulhady4H. Salah5S. I. Nasef6E. Abd El-Latif7Y. Farag8M. Eissa9S. Esam Maher10A. Radwan11Amira T. El-Shanawany12B. M. Medhat13D. El Mikkawy14D. M. Mosa15G. El Deriny16M. Mortada17N. S. Osman18N. A. Fouad19N. E. Elkaraly20S. S. Mohamed21S. A. Tabra22W. A. Hassan23Y. Amer24M. H. Abu-Zaid25King’s College LondonPediatric Rheumatology, Cairo UniversityPediatric Rheumatology, Cairo UniversityCommunity Medicine and Public Health, Ain Shams UniversityRheumatology and Rehabilitation, Ain Shams UniversityPediatric Rheumatology, Cairo UniversityRheumatology and Rehabilitation, Suez Canal UniversityOphthalmology, Alexandria UniversityPediatric Rheumatology, Cairo UniversityRheumatology, Cairo UniversityPediatric Rheumatology, Minia UniversityRheumatology and Rehabilitation, Sohag UniversityRheumatology and Rehabilitation, Menoufia UniversityRheumatology and Rehabilitation, Cairo UniversityRheumatology and Rehabilitation, Ain Shams UniversityRheumatology, Mansoura UniversityPediatrics, Alexandria UniversityRheumatology and Rehabilitation, Zagazig UniversityPediatrics, Assiut UniversityRheumatology and Rehabilitation, Fayoum UniversityRheumatology and Rehabilitation, Suez Canal UniversityRheumatology and Rehabilitation, Cairo UniversityRheumatology and Rehabilitation, Tanta UniversityRheumatology and Rehabilitation, Benha UniversityRheumatology and Rehabilitation, Zagazig UniversityRheumatology and Rehabilitation Department, Faculty of Medicine, Tanta UniversityAbstract Background These updated guidelines aimed to provide appropriate and convenient guidelines for the treatment of various types of juvenile idiopathic arthritis (JIA). Using the Delphi technique, this study was conducted to reach expert consensus on a treat-to-target management strategy for JIA. According to the PICO (patient/population, intervention, comparison, and outcomes) approach, the preliminary scientific committee identified a total of 17 key clinical questions. To assemble evidence on the advantages and dangers associated with JIA treatments, an evidence-based, systematic literature review was conducted. Researchers and clinicians with experience in JIA management were identified by the core leadership team. To establish a consensus on the management suggestions for JIA patients, a Delphi approach (2 rounds) was used. Results An online survey was applied to the expert panel (n = 27), and 26 of them completed both rounds. At the conclusion of round 2, a total of eighteen (18) recommendation items were gathered, which were divided into four sections to address the four key JIA categories. The percentage of those who agreed with the recommendations (ranks 7–9) ranged from 83.2 to 100% (average 86.8%). The phrasing of all 18 clinical standards identified by the scientific committee was agreed upon (i.e. 75% of respondents strongly agreed or agreed). Algorithms have been proposed for the management of JIA polyarthritis, oligoarthritis, and systemic JIA. Conclusion A wide and representative panel of experts initiated a consensus about the management of JIA. The created guidelines give a complete approach to the management of JIA for all healthcare professionals involved in its management, as well as a means of monitoring and evaluating these guidelines on a regular basis.https://doi.org/10.1186/s43166-022-00125-1GuidelinesJIAArthritisMethotrexateBiologic therapyEgypt
spellingShingle Y. El Miedany
S. Salah
H. Lotfy
M. El Gaafary
H. Abdulhady
H. Salah
S. I. Nasef
E. Abd El-Latif
Y. Farag
M. Eissa
S. Esam Maher
A. Radwan
Amira T. El-Shanawany
B. M. Medhat
D. El Mikkawy
D. M. Mosa
G. El Deriny
M. Mortada
N. S. Osman
N. A. Fouad
N. E. Elkaraly
S. S. Mohamed
S. A. Tabra
W. A. Hassan
Y. Amer
M. H. Abu-Zaid
Updated clinical practice treat-to-target guidelines for JIA management: the Egyptian College of Pediatric Rheumatology initiative
Egyptian Rheumatology and Rehabilitation
Guidelines
JIA
Arthritis
Methotrexate
Biologic therapy
Egypt
title Updated clinical practice treat-to-target guidelines for JIA management: the Egyptian College of Pediatric Rheumatology initiative
title_full Updated clinical practice treat-to-target guidelines for JIA management: the Egyptian College of Pediatric Rheumatology initiative
title_fullStr Updated clinical practice treat-to-target guidelines for JIA management: the Egyptian College of Pediatric Rheumatology initiative
title_full_unstemmed Updated clinical practice treat-to-target guidelines for JIA management: the Egyptian College of Pediatric Rheumatology initiative
title_short Updated clinical practice treat-to-target guidelines for JIA management: the Egyptian College of Pediatric Rheumatology initiative
title_sort updated clinical practice treat to target guidelines for jia management the egyptian college of pediatric rheumatology initiative
topic Guidelines
JIA
Arthritis
Methotrexate
Biologic therapy
Egypt
url https://doi.org/10.1186/s43166-022-00125-1
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