Medicinal Profile, Phytochemistry, and Pharmacological Activities of Murraya koenigii and its Primary Bioactive Compounds
The discovery of several revitalizing molecules that can stop or reduce the pathology of a wide range of diseases will be considered a major breakthrough of the present time. Available synthetic compounds may provoke side effects and health issues, which heightens the need for molecules from plants...
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MDPI AG
2020-01-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/9/2/101 |
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| author | Rengasamy Balakrishnan Dhanraj Vijayraja Song-Hee Jo Palanivel Ganesan In Su-Kim Dong-Kug Choi |
| author_facet | Rengasamy Balakrishnan Dhanraj Vijayraja Song-Hee Jo Palanivel Ganesan In Su-Kim Dong-Kug Choi |
| author_sort | Rengasamy Balakrishnan |
| collection | DOAJ |
| description | The discovery of several revitalizing molecules that can stop or reduce the pathology of a wide range of diseases will be considered a major breakthrough of the present time. Available synthetic compounds may provoke side effects and health issues, which heightens the need for molecules from plants and other natural resources under discovery as potential methods of replacing synthetic compounds. In traditional medicinal therapies, several plant extracts and phytochemicals have been reported to impart remedial effects as better alternatives. <i>Murraya</i><i> </i><i>koenigii</i> (<i>M.</i> <i>koenigii</i>)<i> </i>belongs to the Rutaceae family, which is commonly used as a medicinally important herb of Indian origin in the Ayurvedic system of medicine. Previous reports have demonstrated that the leaves, roots, and bark of this plant are rich sources of carbazole alkaloids, which produce potent biological activities and pharmacological effects. These include antioxidant, antidiabetic, anti-inflammatory, antitumor, and neuroprotective activities. The present review provides insight into the major components of <i>M.</i> <i>koenigii</i> and their pharmacological activities against different pathological conditions. The review also emphasizes the need for more research on the molecular basis of such activity in various cellular and animal models to validate the efficacy of <i>M.</i> <i>koenigii</i> and its derivatives as potent therapeutic agents. |
| first_indexed | 2024-03-12T09:40:03Z |
| format | Article |
| id | doaj.art-5d39d0a75b43402f8feb86fc0842e299 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-12T09:40:03Z |
| publishDate | 2020-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-5d39d0a75b43402f8feb86fc0842e2992023-09-02T13:20:25ZengMDPI AGAntioxidants2076-39212020-01-019210110.3390/antiox9020101antiox9020101Medicinal Profile, Phytochemistry, and Pharmacological Activities of Murraya koenigii and its Primary Bioactive CompoundsRengasamy Balakrishnan0Dhanraj Vijayraja1Song-Hee Jo2Palanivel Ganesan3In Su-Kim4Dong-Kug Choi5Department of Applied Life Sciences and Integrated Bioscience, Graduate School, Konkuk University, Chungju 27478, KoreaDepartment of Biochemistry, Rev. Jacob Memorial Christian College, Ambilikkai-624612, Tamilnadu, IndiaDepartment of Applied Life Sciences and Integrated Bioscience, Graduate School, Konkuk University, Chungju 27478, KoreaDepartment of Integrated Bio Science and Biotechnology, College of Biomedical and Health Science, Nanotechnology Research Center, Konkuk University, Chungju, 27478, KoreaDepartment of Applied Life Sciences and Integrated Bioscience, Graduate School, Konkuk University, Chungju 27478, KoreaDepartment of Applied Life Sciences and Integrated Bioscience, Graduate School, Konkuk University, Chungju 27478, KoreaThe discovery of several revitalizing molecules that can stop or reduce the pathology of a wide range of diseases will be considered a major breakthrough of the present time. Available synthetic compounds may provoke side effects and health issues, which heightens the need for molecules from plants and other natural resources under discovery as potential methods of replacing synthetic compounds. In traditional medicinal therapies, several plant extracts and phytochemicals have been reported to impart remedial effects as better alternatives. <i>Murraya</i><i> </i><i>koenigii</i> (<i>M.</i> <i>koenigii</i>)<i> </i>belongs to the Rutaceae family, which is commonly used as a medicinally important herb of Indian origin in the Ayurvedic system of medicine. Previous reports have demonstrated that the leaves, roots, and bark of this plant are rich sources of carbazole alkaloids, which produce potent biological activities and pharmacological effects. These include antioxidant, antidiabetic, anti-inflammatory, antitumor, and neuroprotective activities. The present review provides insight into the major components of <i>M.</i> <i>koenigii</i> and their pharmacological activities against different pathological conditions. The review also emphasizes the need for more research on the molecular basis of such activity in various cellular and animal models to validate the efficacy of <i>M.</i> <i>koenigii</i> and its derivatives as potent therapeutic agents.https://www.mdpi.com/2076-3921/9/2/101murraya koenigiiantioxidantbioactive compoundspharmacological activitytraditional medicine |
| spellingShingle | Rengasamy Balakrishnan Dhanraj Vijayraja Song-Hee Jo Palanivel Ganesan In Su-Kim Dong-Kug Choi Medicinal Profile, Phytochemistry, and Pharmacological Activities of Murraya koenigii and its Primary Bioactive Compounds Antioxidants murraya koenigii antioxidant bioactive compounds pharmacological activity traditional medicine |
| title | Medicinal Profile, Phytochemistry, and Pharmacological Activities of Murraya koenigii and its Primary Bioactive Compounds |
| title_full | Medicinal Profile, Phytochemistry, and Pharmacological Activities of Murraya koenigii and its Primary Bioactive Compounds |
| title_fullStr | Medicinal Profile, Phytochemistry, and Pharmacological Activities of Murraya koenigii and its Primary Bioactive Compounds |
| title_full_unstemmed | Medicinal Profile, Phytochemistry, and Pharmacological Activities of Murraya koenigii and its Primary Bioactive Compounds |
| title_short | Medicinal Profile, Phytochemistry, and Pharmacological Activities of Murraya koenigii and its Primary Bioactive Compounds |
| title_sort | medicinal profile phytochemistry and pharmacological activities of murraya koenigii and its primary bioactive compounds |
| topic | murraya koenigii antioxidant bioactive compounds pharmacological activity traditional medicine |
| url | https://www.mdpi.com/2076-3921/9/2/101 |
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