Influence of Poloxamer 188 on Design and Develop-ment of Second Generation PLGA Nanocrystals of Metformin Hydrochloride

Influence of Poloxamer 188 on Design and Develop-ment of Second Generation PLGA Nanocrystals of Metformin Hydrochloride

The poly(D,L-lactide-co-glycolide) (PLGA) based second-generation nanocrystals prepared by modified nanoprecipitation method, is the method of choice for encapsulation of both lipophilic and hydrophilic drugs. In this study, nanoprecipitation technique was adopted to develop second generation nanocr...

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Bibliographic Details
Main Authors: Bibhu Prasad Panda, Rachna Krishnamoorthy, Naveen Kumar Hawala Shivashekaregowda, Sujata Patnaik
Format: Article
Language:English
Published: Tsinghua University Press 2018-12-01
Series:Nano Biomedicine and Engineering
Subjects:
nanoprecipitation
metformin hcl
poloxmer 188
plga polymer
plga second-generation nanocrystals
Online Access:https://www.sciopen.com/article/10.5101/nbe.v10i4.p334-343

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