Ventilatory Management of Patients with Acute Respiratory Distress Syndrome Due to SARS-CoV-2
The emergence of the new SARS-CoV-2 in December 2019 caused a worldwide pandemic of the resultant disease, COVID-19. There was a massive surge in admissions to intensive care units (ICU), notably of patients with hypoxaemic acute respiratory failure. In these patients, optimal oxygen therapy was cru...
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Format: | Article |
Language: | English |
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MDPI AG
2023-12-01
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Series: | Journal of Clinical Medicine |
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Online Access: | https://www.mdpi.com/2077-0383/12/24/7509 |
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author | Marine Jacquier Marie Labruyère Fiona Ecarnot Jean-Baptiste Roudaut Pascal Andreu Pierre Voizeux Quentin Save Romain Pedri Jean-Philippe Rigaud Jean-Pierre Quenot |
author_facet | Marine Jacquier Marie Labruyère Fiona Ecarnot Jean-Baptiste Roudaut Pascal Andreu Pierre Voizeux Quentin Save Romain Pedri Jean-Philippe Rigaud Jean-Pierre Quenot |
author_sort | Marine Jacquier |
collection | DOAJ |
description | The emergence of the new SARS-CoV-2 in December 2019 caused a worldwide pandemic of the resultant disease, COVID-19. There was a massive surge in admissions to intensive care units (ICU), notably of patients with hypoxaemic acute respiratory failure. In these patients, optimal oxygen therapy was crucial. In this article, we discuss tracheal intubation to provide mechanical ventilation in patients with hypoxaemic acute respiratory failure due to SARS-CoV-2. We first describe the pathophysiology of respiratory anomalies leading to acute respiratory distress syndrome (ARDS) due to infection with SARS-CoV-2, and then briefly review management, focusing particularly on the ventilation strategy. Overall, the ventilatory management of ARDS due to SARS-CoV-2 infection is largely the same as that applied in ARDS from other causes, and lung-protective ventilation is recommended. The difference lies in the initial clinical presentation, with profound hypoxaemia often observed concomitantly with near-normal pulmonary compliance. |
first_indexed | 2024-03-08T20:39:47Z |
format | Article |
id | doaj.art-5d460b5aa41242228ec1853a98a93a5a |
institution | Directory Open Access Journal |
issn | 2077-0383 |
language | English |
last_indexed | 2024-03-08T20:39:47Z |
publishDate | 2023-12-01 |
publisher | MDPI AG |
record_format | Article |
series | Journal of Clinical Medicine |
spelling | doaj.art-5d460b5aa41242228ec1853a98a93a5a2023-12-22T14:16:49ZengMDPI AGJournal of Clinical Medicine2077-03832023-12-011224750910.3390/jcm12247509Ventilatory Management of Patients with Acute Respiratory Distress Syndrome Due to SARS-CoV-2Marine Jacquier0Marie Labruyère1Fiona Ecarnot2Jean-Baptiste Roudaut3Pascal Andreu4Pierre Voizeux5Quentin Save6Romain Pedri7Jean-Philippe Rigaud8Jean-Pierre Quenot9Department of Intensive Care, François Mitterrand, University Hospital, 21000 Dijon, FranceDepartment of Intensive Care, François Mitterrand, University Hospital, 21000 Dijon, FranceDepartment of Cardiology, University Hospital Besancon, 25030 Besançon, FranceDepartment of Intensive Care, François Mitterrand, University Hospital, 21000 Dijon, FranceDepartment of Intensive Care, François Mitterrand, University Hospital, 21000 Dijon, FranceDepartment of Intensive Care, François Mitterrand, University Hospital, 21000 Dijon, FranceDepartment of Intensive Care, François Mitterrand, University Hospital, 21000 Dijon, FranceDepartment of Intensive Care, François Mitterrand, University Hospital, 21000 Dijon, FranceDepartment of Intensive Care, Centre Hospitalier de Dieppe, 76202 Dieppe, FranceDepartment of Intensive Care, François Mitterrand, University Hospital, 21000 Dijon, FranceThe emergence of the new SARS-CoV-2 in December 2019 caused a worldwide pandemic of the resultant disease, COVID-19. There was a massive surge in admissions to intensive care units (ICU), notably of patients with hypoxaemic acute respiratory failure. In these patients, optimal oxygen therapy was crucial. In this article, we discuss tracheal intubation to provide mechanical ventilation in patients with hypoxaemic acute respiratory failure due to SARS-CoV-2. We first describe the pathophysiology of respiratory anomalies leading to acute respiratory distress syndrome (ARDS) due to infection with SARS-CoV-2, and then briefly review management, focusing particularly on the ventilation strategy. Overall, the ventilatory management of ARDS due to SARS-CoV-2 infection is largely the same as that applied in ARDS from other causes, and lung-protective ventilation is recommended. The difference lies in the initial clinical presentation, with profound hypoxaemia often observed concomitantly with near-normal pulmonary compliance.https://www.mdpi.com/2077-0383/12/24/7509managementacute respiratory distress syndromeCOVID-19ICUSARS-CoV-2 |
spellingShingle | Marine Jacquier Marie Labruyère Fiona Ecarnot Jean-Baptiste Roudaut Pascal Andreu Pierre Voizeux Quentin Save Romain Pedri Jean-Philippe Rigaud Jean-Pierre Quenot Ventilatory Management of Patients with Acute Respiratory Distress Syndrome Due to SARS-CoV-2 Journal of Clinical Medicine management acute respiratory distress syndrome COVID-19 ICU SARS-CoV-2 |
title | Ventilatory Management of Patients with Acute Respiratory Distress Syndrome Due to SARS-CoV-2 |
title_full | Ventilatory Management of Patients with Acute Respiratory Distress Syndrome Due to SARS-CoV-2 |
title_fullStr | Ventilatory Management of Patients with Acute Respiratory Distress Syndrome Due to SARS-CoV-2 |
title_full_unstemmed | Ventilatory Management of Patients with Acute Respiratory Distress Syndrome Due to SARS-CoV-2 |
title_short | Ventilatory Management of Patients with Acute Respiratory Distress Syndrome Due to SARS-CoV-2 |
title_sort | ventilatory management of patients with acute respiratory distress syndrome due to sars cov 2 |
topic | management acute respiratory distress syndrome COVID-19 ICU SARS-CoV-2 |
url | https://www.mdpi.com/2077-0383/12/24/7509 |
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