Neutrophil Extracellular Traps Induced by Shiga Toxin and Lipopolysaccharide-Treated Platelets Exacerbate Endothelial Cell Damage

Neutrophil Extracellular Traps Induced by Shiga Toxin and Lipopolysaccharide-Treated Platelets Exacerbate Endothelial Cell Damage

Hemolytic uremic syndrome (HUS) is the most common cause of acute renal failure in the pediatric population. The etiology of HUS is linked to Gram-negative, Shiga toxin (Stx)-producing enterohemorrhagic bacterial infections. While the effect of Stx is focused on endothelial damage of renal glomerulu...

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Main Authors: Verónica Inés Landoni, Jose R. Pittaluga, Agostina Carestia, Luis Alejandro Castillo, Marcelo de Campos Nebel, Daiana Martire-Greco, Federico Birnberg-Weiss, Mirta Schattner, Pablo Schierloh, Gabriela C. Fernández
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
endothelial cell damage
netosis
platelets
Shiga toxin
LPS
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.897019/full

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