Characterization of Calcium Phosphate Spherical Particles in the Subretinal Pigment Epithelium–Basal Lamina Space in Aged Human Eyes

Characterization of Calcium Phosphate Spherical Particles in the Subretinal Pigment Epithelium–Basal Lamina Space in Aged Human Eyes

Purpose: Micrometer-sized spherules formed of hydroxyapatite or whitlockite were identified within extracellular deposits that accumulate in the space between the basal lamina (BL) of retinal pigment epithelium (RPE) and the inner collagenous layer of Bruch’s membrane (sub-RPE–BL space). This invest...

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Bibliographic Details
Main Authors: Matthew G. Pilgrim, PhD, Salma Marouf, MD, Sarah Fearn, PhD, Lajos Csincsik, PhD, Elod Kortvely, PhD, Jonathan C. Knowles, PhD, Goldis Malek, PhD, Richard B. Thompson, PhD, Imre Lengyel, PhD
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Ophthalmology Science
Subjects:
Choroid
Drusen
Ectopic calcification
Retina
Spherical particle
Sub–retinal pigment epithelium
Online Access:http://www.sciencedirect.com/science/article/pii/S2666914521000518

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