Semantic-Aware Graph Convolutional Networks for Clinical Auxiliary Diagnosis and Treatment of Traditional Chinese Medicine

Traditional Chinese Medicine (TCM) clinical informatization focuses on serving user-oriented health knowledge and facilitating online diagnosis. Regularities are hidden in clinical knowledge play a significant role in the improvement of the TCM informatization service. However, many regularities can...

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Main Authors: Chunyang Ruan, Yingpei Wu, Yun Yang, Guangsheng Luo
Format: Article
Language:English
Published: IEEE 2021-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/9312604/
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author Chunyang Ruan
Yingpei Wu
Yun Yang
Guangsheng Luo
author_facet Chunyang Ruan
Yingpei Wu
Yun Yang
Guangsheng Luo
author_sort Chunyang Ruan
collection DOAJ
description Traditional Chinese Medicine (TCM) clinical informatization focuses on serving user-oriented health knowledge and facilitating online diagnosis. Regularities are hidden in clinical knowledge play a significant role in the improvement of the TCM informatization service. However, many regularities can hardly be discovered because of specific data-challenges in TCM prescriptions at present. Therefore, in this article, we propose an end-to-end model, called Semantic-aware Graph Convolutional Networks (SaGCN) model, to learn the latent regularities in three steps: (1) We first construct a heterogeneous graph based on prescriptions; (2) We stack Semantic-aware graph convolution to learn effective low-dimensional representations of nodes by meta-graphs and self-attention; (3) With the learned representations, we can detect regularities accurately by clustering and linked prediction. To the best of our knowledge, this is the first study to use metagraph and graph convolutional networks for modeling TCM clinical data and diagnosis prediction. Experimental results on three real datasets demonstrate SaGCN outperforms the state-of-the-art models for clinical auxiliary diagnosis and treatment.
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spelling doaj.art-5d4b99b6ba374135b6979ffe44a3a8182022-12-22T04:25:38ZengIEEEIEEE Access2169-35362021-01-0198797880710.1109/ACCESS.2020.30489329312604Semantic-Aware Graph Convolutional Networks for Clinical Auxiliary Diagnosis and Treatment of Traditional Chinese MedicineChunyang Ruan0https://orcid.org/0000-0002-6280-0148Yingpei Wu1Yun Yang2Guangsheng Luo3https://orcid.org/0000-0003-4278-2971Department of Data Science and Big Data Technology, School of Economics and Finance, Shanghai International Studies University, Shanghai, ChinaSchool of Software Engineering, Fudan University, Shanghai, ChinaDepartment of Oncology, Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaDepartment of Data Science and Big Data Technology, School of Economics and Finance, Shanghai International Studies University, Shanghai, ChinaTraditional Chinese Medicine (TCM) clinical informatization focuses on serving user-oriented health knowledge and facilitating online diagnosis. Regularities are hidden in clinical knowledge play a significant role in the improvement of the TCM informatization service. However, many regularities can hardly be discovered because of specific data-challenges in TCM prescriptions at present. Therefore, in this article, we propose an end-to-end model, called Semantic-aware Graph Convolutional Networks (SaGCN) model, to learn the latent regularities in three steps: (1) We first construct a heterogeneous graph based on prescriptions; (2) We stack Semantic-aware graph convolution to learn effective low-dimensional representations of nodes by meta-graphs and self-attention; (3) With the learned representations, we can detect regularities accurately by clustering and linked prediction. To the best of our knowledge, this is the first study to use metagraph and graph convolutional networks for modeling TCM clinical data and diagnosis prediction. Experimental results on three real datasets demonstrate SaGCN outperforms the state-of-the-art models for clinical auxiliary diagnosis and treatment.https://ieeexplore.ieee.org/document/9312604/Tranditional Chinese medicineclinical knowledge discoverymetagraphgraph convolutional networks
spellingShingle Chunyang Ruan
Yingpei Wu
Yun Yang
Guangsheng Luo
Semantic-Aware Graph Convolutional Networks for Clinical Auxiliary Diagnosis and Treatment of Traditional Chinese Medicine
IEEE Access
Tranditional Chinese medicine
clinical knowledge discovery
metagraph
graph convolutional networks
title Semantic-Aware Graph Convolutional Networks for Clinical Auxiliary Diagnosis and Treatment of Traditional Chinese Medicine
title_full Semantic-Aware Graph Convolutional Networks for Clinical Auxiliary Diagnosis and Treatment of Traditional Chinese Medicine
title_fullStr Semantic-Aware Graph Convolutional Networks for Clinical Auxiliary Diagnosis and Treatment of Traditional Chinese Medicine
title_full_unstemmed Semantic-Aware Graph Convolutional Networks for Clinical Auxiliary Diagnosis and Treatment of Traditional Chinese Medicine
title_short Semantic-Aware Graph Convolutional Networks for Clinical Auxiliary Diagnosis and Treatment of Traditional Chinese Medicine
title_sort semantic aware graph convolutional networks for clinical auxiliary diagnosis and treatment of traditional chinese medicine
topic Tranditional Chinese medicine
clinical knowledge discovery
metagraph
graph convolutional networks
url https://ieeexplore.ieee.org/document/9312604/
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AT yingpeiwu semanticawaregraphconvolutionalnetworksforclinicalauxiliarydiagnosisandtreatmentoftraditionalchinesemedicine
AT yunyang semanticawaregraphconvolutionalnetworksforclinicalauxiliarydiagnosisandtreatmentoftraditionalchinesemedicine
AT guangshengluo semanticawaregraphconvolutionalnetworksforclinicalauxiliarydiagnosisandtreatmentoftraditionalchinesemedicine