Could internal limiting membrane peeling before Voretigen neparvovec-ryzl subretinal injection prevent focal chorioretinal atrophy?

Could internal limiting membrane peeling before Voretigen neparvovec-ryzl subretinal injection prevent focal chorioretinal atrophy?

Purpose: To report the effect of internal limiting membrane (ILM) peeling prior to Voretigen Neparvovec-ryzl (VN) subretinal injection on focal chorioretinal atrophy development in patients presenting with RPE65-mediated Leber congenital amaurosis (LCA). Design: Retrospective case series. Methods: T...

Full description

Bibliographic Details
Main Authors:	Lea Dormegny, Fouzia Studer, Arnaud Sauer, Laurent Ballonzoli, Claude Speeg-Schatz, Tristan Bourcier, Helene Dollfus, David Gaucher
Format:	Article
Language:	English
Published:	Elsevier 2024-02-01
Series:	Heliyon
Subjects:	Leber congenital amaurosis RPE65-mediated retinal dystrophy Luxturna Gene therapy Retinitis pigmentosa Perifoveal chorioretinal atrophy
Online Access:	http://www.sciencedirect.com/science/article/pii/S240584402401185X

Similar Items

Chorioretinal atrophy following voretigene neparvovec despite the presence of fundus autofluorescence
by: Masha Kolesnikova, et al.
Published: (2022-11-01)

Response to comment on: Could internal limiting membrane peeling before Voretigen Neparvovec-ryzl subretinal injection prevent focal chorioretinal atrophy?
by: Lea Dormegny, et al.
Published: (2024-10-01)

Gene Therapy with Voretigene Neparvovec Improves Vision and Partially Restores Electrophysiological Function in Pre-School Children with Leber Congenital Amaurosis
by: Maximilian J. Gerhardt, et al.
Published: (2022-12-01)

Bilateral exudative retinal detachments after subretinal gene therapy with voretigene neparvovec-rzyl for RPE65 Leber Congenital Amaurosis
by: Alcina K. Lidder, et al.
Published: (2023-12-01)

First results of long-term follow-up of children in Russia after gene therapy for hereditary retinal dystrophies associated with biallelic mutations in the RPE65 gene
by: V. V. Neroev, et al.
Published: (2023-12-01)

Cas9-targeted-based long-read sequencing for genetic screening of RPE65 locus
by: Cristina Rodilla, et al.
Published: (2024-10-01)

A decision making algorithm for inherited retinal dystrophies, caused by biallelic mutations in the RPE65 gene, in the clinical practice of an ophthalmologist
by: E. I. Saidasheva, et al.
Published: (2022-03-01)

Economic outcomes of centralized procurements of gene therapy for patients with orphan diseases: inherited retinal dystrophy
by: N. А. Avxentyev, et al.
Published: (2022-01-01)

Letter to the Editor of Heliyon: Could internal limiting membrane peeling before Voretigen neparvovec-ryzl subretinal injection prevent focal chorioretinal atrophy?
by: Mirjana Bjeloš, et al.
Published: (2024-11-01)

Cost-effectiveness of voretigene neparvovec in the treatment of patients with inherited retinal disease with RPE65 mutation in Switzerland
by: Arjun Bhadhuri, et al.
Published: (2022-06-01)

Prospects for the diagnosis and gene therapy of inherited retinal dystrophies caused by biallelic mutations in the RPE65 gene
by: V. V. Neroev, et al.
Published: (2021-09-01)

Development of a novel prediction model based on protein structure for identifying RPE65-associated inherited retinal disease (IRDs) of missense variants
by: Jiawen Wu, et al.
Published: (2023-08-01)

Extensive genic and allelic heterogeneity underlying inherited retinal dystrophies in Mexican patients molecularly analyzed by next‐generation sequencing
by: Juan C. Zenteno, et al.
Published: (2020-01-01)

A novel RPE65 variant p.(Ala391Asp) in Leber congenital amaurosis: a case report and literature review in Japan
by: Natsuki Higa, et al.
Published: (2024-09-01)

Real-World Safety and Effectiveness of Voretigene Neparvovec: Results up to 2 Years from the Prospective, Registry-Based PERCEIVE Study
by: M. Dominik Fischer, et al.
Published: (2024-01-01)

CRISPR-Cas9 correction of a nonsense mutation in LCA5 rescues lebercilin expression and localization in human retinal organoids
by: Tess A.V. Afanasyeva, et al.
Published: (2023-06-01)

The Predicted Splicing Variant c.11+5G>A in <i>RPE65</i> Leads to a Reduction in mRNA Expression in a Cell-Specific Manner
by: Irene Vázquez-Domínguez, et al.
Published: (2022-11-01)

Large Animal Models of Inherited Retinal Degenerations: A Review
by: Paige A. Winkler, et al.
Published: (2020-04-01)

The spectrum of COVID-19-associated chorioretinal vasculopathy
by: Piero Carletti, et al.
Published: (2023-09-01)

A Korean Patient With Leber Congenital Amaurosis and a Homozygous RPE65 Variant Originating From a Paternal Uniparental Isodisomy
by: Hane Lee, et al.
Published: (2025-01-01)

A Comprehensive Study of the Retinal Phenotype of Rpe65-Deficient Dogs
by: Matthew J Annear, et al.
Published: (2021-01-01)

Dynamics of ultrastructural changes in the chorioretinal complex of rat eyes induced by high dose of methanol
by: N. Molchanyuk
Published: (2016-11-01)

Pigmented Paravenous Chorioretinal Atrophy and Mucopolysaccharidosis: A Case Report
by: Zineb Algouti, et al.
Published: (2024-04-01)

The Outcome of Surgeries Performed for Retinal Detachment Associated with Chorioretinal Coloboma
by: Muhammad Tariq Khan, et al.
Published: (2023-12-01)

Comprehensive analysis of two hotspot codons in the TUBB4B gene and associated phenotypes
by: Jan-Philipp Bodenbender, et al.
Published: (2024-05-01)

Retinal Map of Peripheral Retinal Degenerations and Tears. Part 2. Non-rhegmatogenous Chorioretinal Degenerations
by: V. A. Shaimova, et al.
Published: (2024-10-01)

Chorioretinal Biopsy in an Immunocompromised Patient with Subretinal Mass
by: Somanus Thoongsuwan, et al.
Published: (2020-07-01)

A Systematic Review and Meta-Analyses of Interventional Clinical Trial Studies for Gene Therapies for the Inherited Retinal Degenerations (IRDs)
by: Gearóid P. Tuohy, et al.
Published: (2021-05-01)

Long-Term Follow-Up of a Family with Retinal Dystrophy Caused by RPE65 Mutation
by: Ágnes Jánossy, et al.
Published: (2023-09-01)

Outcomes and Adverse Effects of Voretigene Neparvovec Treatment for Biallelic <i>RPE65</i>-Mediated Inherited Retinal Dystrophies in a Cohort of Patients from a Single Center
by: Peter Kiraly, et al.
Published: (2023-10-01)

Cellular and Molecular Mechanisms of Pathogenesis Underlying Inherited Retinal Dystrophies
by: Andrew Manley, et al.
Published: (2023-02-01)

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss
by: Gayle B. Collin, et al.
Published: (2020-04-01)

Manifestations of systemic disease in the retina and fundus of cats and dogs
by: Billie Beckwith-Cohen, et al.
Published: (2024-02-01)

Spontaneous resolution of acute syphilitic posterior placoid chorioretinitis: reappraisal of the literature and pathogenetic insights
by: Casalino, Giuseppe, et al.
Published: (2020-05-01)

Zebrafish Models of Photoreceptor Dysfunction and Degeneration
by: Nicole C. L. Noel, et al.
Published: (2021-01-01)

Percorso diagnostico-terapeutico e modello organizzativo per l’erogazione della terapia genica nelle distrofie retiniche ereditarie in real-life
by: Francesco Bandello, et al.
Published: (2023-03-01)

A mouse model of cone photoreceptor function loss (cpfl9) with degeneration due to a mutation in Gucy2e
by: Anna S. E. N. Naggert, et al.
Published: (2023-01-01)

Targeting molecular pathways for the treatment of inherited retinal degeneration
by: Meltem Kutluer, et al.
Published: (2020-01-01)

Chickenpox Chorioretinitis with Retinal Exudates and Periphlebitis
by: Hirokuni Kitamei, et al.
Published: (2012-05-01)

Visual function restoration in a mouse model of Leber congenital amaurosis via therapeutic base editing
by: Dong Hyun Jo, et al.
Published: (2023-03-01)