Accidental phosgene gas exposure: A review with background study of 10 cases

Here, authors present a review on clinical presentation and management of exposure of phosgene gas after reviewing the literature by searching with keywords phosgene exposure on Google, Cochrane, Embase and PubMed with a background of experience gained from 10 patients who were admitted to our insti...

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Main Authors: Arvind Kumar Vaish, Shuchi Consul, Avinash Agrawal, Shyam Chand Chaudhary, Manish Gutch, Nirdesh Jain, Mohit Mohan Singh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Journal of Emergencies, Trauma and Shock
Subjects:
Online Access:http://www.onlinejets.org/article.asp?issn=0974-2700;year=2013;volume=6;issue=4;spage=271;epage=275;aulast=Vaish
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author Arvind Kumar Vaish
Shuchi Consul
Avinash Agrawal
Shyam Chand Chaudhary
Manish Gutch
Nirdesh Jain
Mohit Mohan Singh
author_facet Arvind Kumar Vaish
Shuchi Consul
Avinash Agrawal
Shyam Chand Chaudhary
Manish Gutch
Nirdesh Jain
Mohit Mohan Singh
author_sort Arvind Kumar Vaish
collection DOAJ
description Here, authors present a review on clinical presentation and management of exposure of phosgene gas after reviewing the literature by searching with keywords phosgene exposure on Google, Cochrane, Embase and PubMed with a background of experience gained from 10 patients who were admitted to our institute after an accidental phosgene exposure in February 2011 nearby a city in India. Phosgene is a highly toxic gas, occupational workers may have accidental exposure. The gas can also be generated inadvertently during fire involving plastics and other chemicals and solvents containing chlorine, which is of concern to emergency responders. Phosgene inhalation may cause initially symptoms of respiratory tract irritation, patients feel fine thereafter, and then die of choking a day later because of build up of fluid in the lungs (delayed onset non-cardiogenic pulmonary edema). Phosgene exposure is associated with significant morbidity and mortality. Patients with a history of exposure should be admitted to the hospital for a minimum of 24 h for observation because of the potential for delayed onset respiratory failure and acute respiratory distress syndrome.
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spelling doaj.art-5d59b4ce5af44b9ab6eae369e1baa59c2022-12-21T21:14:25ZengWolters Kluwer Medknow PublicationsJournal of Emergencies, Trauma and Shock0974-27002013-01-016427127510.4103/0974-2700.120372Accidental phosgene gas exposure: A review with background study of 10 casesArvind Kumar VaishShuchi ConsulAvinash AgrawalShyam Chand ChaudharyManish GutchNirdesh JainMohit Mohan SinghHere, authors present a review on clinical presentation and management of exposure of phosgene gas after reviewing the literature by searching with keywords phosgene exposure on Google, Cochrane, Embase and PubMed with a background of experience gained from 10 patients who were admitted to our institute after an accidental phosgene exposure in February 2011 nearby a city in India. Phosgene is a highly toxic gas, occupational workers may have accidental exposure. The gas can also be generated inadvertently during fire involving plastics and other chemicals and solvents containing chlorine, which is of concern to emergency responders. Phosgene inhalation may cause initially symptoms of respiratory tract irritation, patients feel fine thereafter, and then die of choking a day later because of build up of fluid in the lungs (delayed onset non-cardiogenic pulmonary edema). Phosgene exposure is associated with significant morbidity and mortality. Patients with a history of exposure should be admitted to the hospital for a minimum of 24 h for observation because of the potential for delayed onset respiratory failure and acute respiratory distress syndrome.http://www.onlinejets.org/article.asp?issn=0974-2700;year=2013;volume=6;issue=4;spage=271;epage=275;aulast=VaishAcute respiratory distress syndromeN-acetyl-cysteinephosgene
spellingShingle Arvind Kumar Vaish
Shuchi Consul
Avinash Agrawal
Shyam Chand Chaudhary
Manish Gutch
Nirdesh Jain
Mohit Mohan Singh
Accidental phosgene gas exposure: A review with background study of 10 cases
Journal of Emergencies, Trauma and Shock
Acute respiratory distress syndrome
N-acetyl-cysteine
phosgene
title Accidental phosgene gas exposure: A review with background study of 10 cases
title_full Accidental phosgene gas exposure: A review with background study of 10 cases
title_fullStr Accidental phosgene gas exposure: A review with background study of 10 cases
title_full_unstemmed Accidental phosgene gas exposure: A review with background study of 10 cases
title_short Accidental phosgene gas exposure: A review with background study of 10 cases
title_sort accidental phosgene gas exposure a review with background study of 10 cases
topic Acute respiratory distress syndrome
N-acetyl-cysteine
phosgene
url http://www.onlinejets.org/article.asp?issn=0974-2700;year=2013;volume=6;issue=4;spage=271;epage=275;aulast=Vaish
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