How to Treat Today? Oral and Facial Cancer-Associated Venous Thromboembolism

The exact incidence of cancer-associated venous thromboembolism (CA-VTE) in patients with oral and facial cancer (OFC) is not exactly known, and this risk is empirically considered to be low. However, this suggestion may result in disease underdiagnosis, prolong the initiation of adequate therapy, a...

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Main Authors: Mária Janíčková, Tomáš Bolek, Lucia Stančiaková, Norbert Nagy, Marián Mokáň, Matej Samoš
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/16/7/1011
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author Mária Janíčková
Tomáš Bolek
Lucia Stančiaková
Norbert Nagy
Marián Mokáň
Matej Samoš
author_facet Mária Janíčková
Tomáš Bolek
Lucia Stančiaková
Norbert Nagy
Marián Mokáň
Matej Samoš
author_sort Mária Janíčková
collection DOAJ
description The exact incidence of cancer-associated venous thromboembolism (CA-VTE) in patients with oral and facial cancer (OFC) is not exactly known, and this risk is empirically considered to be low. However, this suggestion may result in disease underdiagnosis, prolong the initiation of adequate therapy, and consecutively increase CA-VTE-related morbidity and mortality. In addition, there might be specific clinical problems in the treatment of CA-VTE in patients with oral and facial cancer, such as swallowing difficulties, that might limit the possibilities of oral anticoagulation. Finally, there are limited data regarding the optimal treatment of CA-VTE in patients with oral and facial cancer, and this includes data on novel therapeutic strategies, including the use of direct oral anticoagulants. This article reviews current data on the optimal treatment strategy for CA-VTE in patients with OFC.
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spelling doaj.art-5d5ac398e8a44086b967aea82ecc43672023-11-18T20:53:07ZengMDPI AGPharmaceuticals1424-82472023-07-01167101110.3390/ph16071011How to Treat Today? Oral and Facial Cancer-Associated Venous ThromboembolismMária Janíčková0Tomáš Bolek1Lucia Stančiaková2Norbert Nagy3Marián Mokáň4Matej Samoš5Department of Stomatology and Maxillofacial Surgery, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 59 Martin, SlovakiaDepartment of Internal Medicine I, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 59 Martin, SlovakiaNational Centre of Hemostasis and Thrombosis, Department of Hematology and Blood, Transfusion, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 59 Martin, SlovakiaDepartment of Internal Medicine I, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 59 Martin, SlovakiaDepartment of Internal Medicine I, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 59 Martin, SlovakiaDepartment of Internal Medicine I, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 59 Martin, SlovakiaThe exact incidence of cancer-associated venous thromboembolism (CA-VTE) in patients with oral and facial cancer (OFC) is not exactly known, and this risk is empirically considered to be low. However, this suggestion may result in disease underdiagnosis, prolong the initiation of adequate therapy, and consecutively increase CA-VTE-related morbidity and mortality. In addition, there might be specific clinical problems in the treatment of CA-VTE in patients with oral and facial cancer, such as swallowing difficulties, that might limit the possibilities of oral anticoagulation. Finally, there are limited data regarding the optimal treatment of CA-VTE in patients with oral and facial cancer, and this includes data on novel therapeutic strategies, including the use of direct oral anticoagulants. This article reviews current data on the optimal treatment strategy for CA-VTE in patients with OFC.https://www.mdpi.com/1424-8247/16/7/1011oral and facial cancercancer-associated venous thromboembolismdirect oral anticoagulantsparenteral anticoagulation
spellingShingle Mária Janíčková
Tomáš Bolek
Lucia Stančiaková
Norbert Nagy
Marián Mokáň
Matej Samoš
How to Treat Today? Oral and Facial Cancer-Associated Venous Thromboembolism
Pharmaceuticals
oral and facial cancer
cancer-associated venous thromboembolism
direct oral anticoagulants
parenteral anticoagulation
title How to Treat Today? Oral and Facial Cancer-Associated Venous Thromboembolism
title_full How to Treat Today? Oral and Facial Cancer-Associated Venous Thromboembolism
title_fullStr How to Treat Today? Oral and Facial Cancer-Associated Venous Thromboembolism
title_full_unstemmed How to Treat Today? Oral and Facial Cancer-Associated Venous Thromboembolism
title_short How to Treat Today? Oral and Facial Cancer-Associated Venous Thromboembolism
title_sort how to treat today oral and facial cancer associated venous thromboembolism
topic oral and facial cancer
cancer-associated venous thromboembolism
direct oral anticoagulants
parenteral anticoagulation
url https://www.mdpi.com/1424-8247/16/7/1011
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