The Antifungal Itraconazole Is a Potent Inhibitor of Chikungunya Virus Replication

The Antifungal Itraconazole Is a Potent Inhibitor of Chikungunya Virus Replication

Chikungunya virus (CHIKV) is the causative agent of chikungunya fever, a disabling disease that can cause long-term severe arthritis. Since the last large CHIKV outbreak in 2015, the reemergence of the virus represents a serious public health concern. The morbidity associated with viral infection em...

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Bibliographic Details
Main Authors: Lucca R. Policastro, Isabela Dolci, Andre S. Godoy, José V. J. Silva Júnior, Uriel E. A. Ruiz, Igor A. Santos, Ana C. G. Jardim, Kirandeep Samby, Jeremy N. Burrows, Timothy N. C. Wells, Laura H. V. G. Gil, Glaucius Oliva, Rafaela S. Fernandes
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
Chikungunya virus
replicon-based assays
drug development
antiviral
Itraconazole
Online Access:https://www.mdpi.com/1999-4915/14/7/1351

Internet

https://www.mdpi.com/1999-4915/14/7/1351

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