Elevation of inositol pyrophosphate IP7 in the mammalian spinal cord of amyotrophic lateral sclerosis

Elevation of inositol pyrophosphate IP7 in the mammalian spinal cord of amyotrophic lateral sclerosis

BackgroundAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder associated with progressive impairment of spinal motor neurons. Continuous research endeavor is underway to fully understand the molecular mechanisms associating with this disorder. Although several studies have impl...

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Bibliographic Details
Main Authors: Masatoshi Ito, Natsuko Fujii, Saori Kohara, Masayuki Tanaka, Masaki Takao, Ban Mihara, Yuko Saito, Atsushi Mizuma, Taira Nakayama, Shizuka Netsu, Naoto Suzuki, Akiyoshi Kakita, Eiichiro Nagata
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Neurology
Subjects:
amyotrophic lateral sclerosis
inositol pyrophosphate
diphosphoinositol pentakisphosphate
inositol hexakisphosphate
liquid chromatography-tandem mass spectrometry
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1334004/full

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https://www.frontiersin.org/articles/10.3389/fneur.2023.1334004/full

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