Synthesis and biological activity of rhodanine-furan conjugates: A review
Rhodanines are recognized as privileged heterocycles in medicinal chemistry. The main achievements include the development of drug-like molecules with numerous biological activities as well as approved drugs. The Furan nucleus is considered one of the promising heterocyclic cores in medicin...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Growing Science
2024-01-01
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| Series: | Current Chemistry Letters |
| Online Access: | http://www.growingscience.com/ccl/Vol13/ccl_2023_79.pdf |
| _version_ | 1797376634784841728 |
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| author | uliia Matiichuk Iryna Drapak Natalia Darmograi Nataliia Bartoshyk Yana Drapak Vasyl Matiychuk |
| author_facet | uliia Matiichuk Iryna Drapak Natalia Darmograi Nataliia Bartoshyk Yana Drapak Vasyl Matiychuk |
| author_sort | uliia Matiichuk |
| collection | DOAJ |
| description | Rhodanines are recognized as privileged heterocycles in medicinal chemistry. The main achievements include the development of drug-like molecules with numerous biological activities as well as approved drugs. The Furan nucleus is considered one of the promising heterocyclic cores in medicinal chemistry that showed numerous ranges of activity. The combination of several heterocycles in a one molecule commonly provides much more interest in the enhanced activity profile of its analogs than their parent separate constituents. Such conjugates are promising objects for modern medicinal chemistry. In this review paper recent advances in the synthesis and biological activities rhodanine-furan conjugates which its application in the different field of drug discovery. |
| first_indexed | 2024-03-08T19:41:29Z |
| format | Article |
| id | doaj.art-5d65b2052e4d4eb5afc431480e0e691b |
| institution | Directory Open Access Journal |
| issn | 1927-7296 1927-730X |
| language | English |
| last_indexed | 2024-03-08T19:41:29Z |
| publishDate | 2024-01-01 |
| publisher | Growing Science |
| record_format | Article |
| series | Current Chemistry Letters |
| spelling | doaj.art-5d65b2052e4d4eb5afc431480e0e691b2023-12-25T05:27:26ZengGrowing ScienceCurrent Chemistry Letters1927-72961927-730X2024-01-0113228730210.5267/j.ccl.2023.12.003Synthesis and biological activity of rhodanine-furan conjugates: A reviewuliia MatiichukIryna DrapakNatalia DarmograiNataliia BartoshykYana DrapakVasyl Matiychuk Rhodanines are recognized as privileged heterocycles in medicinal chemistry. The main achievements include the development of drug-like molecules with numerous biological activities as well as approved drugs. The Furan nucleus is considered one of the promising heterocyclic cores in medicinal chemistry that showed numerous ranges of activity. The combination of several heterocycles in a one molecule commonly provides much more interest in the enhanced activity profile of its analogs than their parent separate constituents. Such conjugates are promising objects for modern medicinal chemistry. In this review paper recent advances in the synthesis and biological activities rhodanine-furan conjugates which its application in the different field of drug discovery.http://www.growingscience.com/ccl/Vol13/ccl_2023_79.pdf |
| spellingShingle | uliia Matiichuk Iryna Drapak Natalia Darmograi Nataliia Bartoshyk Yana Drapak Vasyl Matiychuk Synthesis and biological activity of rhodanine-furan conjugates: A review Current Chemistry Letters |
| title | Synthesis and biological activity of rhodanine-furan conjugates: A review |
| title_full | Synthesis and biological activity of rhodanine-furan conjugates: A review |
| title_fullStr | Synthesis and biological activity of rhodanine-furan conjugates: A review |
| title_full_unstemmed | Synthesis and biological activity of rhodanine-furan conjugates: A review |
| title_short | Synthesis and biological activity of rhodanine-furan conjugates: A review |
| title_sort | synthesis and biological activity of rhodanine furan conjugates a review |
| url | http://www.growingscience.com/ccl/Vol13/ccl_2023_79.pdf |
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