Nocturia independently predicts left ventricular hypertrophy and left atrial enlargement among patients with cardiac symptoms
Abstract Nocturia can be caused by urological disorders and systemic diseases, including heart diseases. We aimed to investigate the relationship between nocturia and structural abnormalities on echocardiography. Adult patients who underwent echocardiography for cardiac symptoms or heart murmur or h...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-09-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-19190-9 |
| _version_ | 1811274877653483520 |
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| author | Kuo-Wei Kao Weiming Cheng Ching-Ju Wu Yu-Hua Fan |
| author_facet | Kuo-Wei Kao Weiming Cheng Ching-Ju Wu Yu-Hua Fan |
| author_sort | Kuo-Wei Kao |
| collection | DOAJ |
| description | Abstract Nocturia can be caused by urological disorders and systemic diseases, including heart diseases. We aimed to investigate the relationship between nocturia and structural abnormalities on echocardiography. Adult patients who underwent echocardiography for cardiac symptoms or heart murmur or had a history of structural heart disease were included. The voiding times during sleep hours were collected prospectively. Univariate and multivariate analyses were performed to evaluate the predictive value of bothersome nocturia (nocturia ≥ 2) on echocardiographic abnormalities. Of 299 patients, 182 (60.9%) reported bothersome nocturia. In patients aged ≥ 65 years, hypertension and left atrial enlargement (LAE) were associated with higher occurrences of bothersome nocturia. On multivariate analysis, bothersome nocturia was a predictive factor of LAE (odds ratio [OR] 2.453, 95% confidence interval [CI] 1.363–4.416, p = 0.003). Moreover, bothersome nocturia could predict both LAE and left ventricular hypertrophy (LVH) (OR 2.285, 95% CI 1.151–4.536, p = 0.018; OR 2.056, 95% CI 1.025–4.124, p = 0.043) in the elderly. Older age, hypertension, and LAE were risk factors for bothersome nocturia. Moreover, bothersome nocturia was predictive of LAE and LVH in the elderly. Patients with bothersome nocturia without other significant lower urinary tract symptoms should be referred to cardiologists. |
| first_indexed | 2024-04-12T23:28:08Z |
| format | Article |
| id | doaj.art-5d661a8a87b4446b84e045d7eaf737d5 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-12T23:28:08Z |
| publishDate | 2022-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-5d661a8a87b4446b84e045d7eaf737d52022-12-22T03:12:21ZengNature PortfolioScientific Reports2045-23222022-09-011211710.1038/s41598-022-19190-9Nocturia independently predicts left ventricular hypertrophy and left atrial enlargement among patients with cardiac symptomsKuo-Wei Kao0Weiming Cheng1Ching-Ju Wu2Yu-Hua Fan3Division of Urology, Department of Surgery, Taipei City Hospital, Renai BranchDivision of Urology, Department of Surgery, Taipei City Hospital, Zhongxiao BranchDivision of Cardiology, Department of Medicine, Taipei City Hospital, Zhongxiao BranchDepartment of Urology, College of Medicine, National Yang Ming Chiao Tung UniversityAbstract Nocturia can be caused by urological disorders and systemic diseases, including heart diseases. We aimed to investigate the relationship between nocturia and structural abnormalities on echocardiography. Adult patients who underwent echocardiography for cardiac symptoms or heart murmur or had a history of structural heart disease were included. The voiding times during sleep hours were collected prospectively. Univariate and multivariate analyses were performed to evaluate the predictive value of bothersome nocturia (nocturia ≥ 2) on echocardiographic abnormalities. Of 299 patients, 182 (60.9%) reported bothersome nocturia. In patients aged ≥ 65 years, hypertension and left atrial enlargement (LAE) were associated with higher occurrences of bothersome nocturia. On multivariate analysis, bothersome nocturia was a predictive factor of LAE (odds ratio [OR] 2.453, 95% confidence interval [CI] 1.363–4.416, p = 0.003). Moreover, bothersome nocturia could predict both LAE and left ventricular hypertrophy (LVH) (OR 2.285, 95% CI 1.151–4.536, p = 0.018; OR 2.056, 95% CI 1.025–4.124, p = 0.043) in the elderly. Older age, hypertension, and LAE were risk factors for bothersome nocturia. Moreover, bothersome nocturia was predictive of LAE and LVH in the elderly. Patients with bothersome nocturia without other significant lower urinary tract symptoms should be referred to cardiologists.https://doi.org/10.1038/s41598-022-19190-9 |
| spellingShingle | Kuo-Wei Kao Weiming Cheng Ching-Ju Wu Yu-Hua Fan Nocturia independently predicts left ventricular hypertrophy and left atrial enlargement among patients with cardiac symptoms Scientific Reports |
| title | Nocturia independently predicts left ventricular hypertrophy and left atrial enlargement among patients with cardiac symptoms |
| title_full | Nocturia independently predicts left ventricular hypertrophy and left atrial enlargement among patients with cardiac symptoms |
| title_fullStr | Nocturia independently predicts left ventricular hypertrophy and left atrial enlargement among patients with cardiac symptoms |
| title_full_unstemmed | Nocturia independently predicts left ventricular hypertrophy and left atrial enlargement among patients with cardiac symptoms |
| title_short | Nocturia independently predicts left ventricular hypertrophy and left atrial enlargement among patients with cardiac symptoms |
| title_sort | nocturia independently predicts left ventricular hypertrophy and left atrial enlargement among patients with cardiac symptoms |
| url | https://doi.org/10.1038/s41598-022-19190-9 |
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