Dimensionless parameter predicts bacterial prodrug success
Abstract Understanding mechanisms of antibiotic failure is foundational to combating the growing threat of multidrug‐resistant bacteria. Prodrugs—which are converted into a pharmacologically active compound after administration—represent a growing class of therapeutics for treating bacterial infecti...
| Main Authors: | Brandon Alexander Holt, McKenzie Tuttle, Yilin Xu, Melanie Su, Joachim J Røise, Xioajian Wang, Niren Murthy, Gabriel A Kwong |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2022-01-01
|
| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/msb.202110495 |
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