Personality dysfunction in opiate addicts on opioid substitution treatment and the risk of HCV infection
BackgroundImpulsivity, affective instability, and neglect of oneself and other people's safety as symptoms of personality dysfunction are associated with risky behaviors regarding the transmission of infectious diseases either sexually or by intravenous drug abuse.ObjectiveThe aim of this study...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2022.1009413/full |
| _version_ | 1811210444895944704 |
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| author | Siniša Skočibušić Nera Zivlak-Radulović Mevludin Hasanović Hassan Awad Dragana Karan-Križanac Nermana Mehić-Basara Tomislav Rukavina |
| author_facet | Siniša Skočibušić Nera Zivlak-Radulović Mevludin Hasanović Hassan Awad Dragana Karan-Križanac Nermana Mehić-Basara Tomislav Rukavina |
| author_sort | Siniša Skočibušić |
| collection | DOAJ |
| description | BackgroundImpulsivity, affective instability, and neglect of oneself and other people's safety as symptoms of personality dysfunction are associated with risky behaviors regarding the transmission of infectious diseases either sexually or by intravenous drug abuse.ObjectiveThe aim of this study was to analyze the association between hepatitis C virus (HCV) infection and personality dysfunction in opiate addicts on opioid substitution treatment.MethodsThis was a cross-sectional, observational investigation of patients over 18 years of age who were actively participating in opioid substitution treatment at five centers in Bosnia and Herzegovina. The occurrence of HCV infection was the primary study outcome, and personality functioning, the main independent variable, was assessed using the Severity Indices of Personality Problems (SIPP−118) questionnaire. The association between scores of personality functioning domains items and HCV infection status was determined by binary logistic regression analysis.ResultsPatients on opioid substitution therapy with HCV infection more frequently had personality disorders (OR 2.168, 95% CI 1.161–4.05) and were treated longer than patients without HCV infection (OR 1.076, 95% CI 1.015–1.14). HCV infection was associated with lower self-respect (OR 0.946, 95% CI 0.906–0.988), decreased capacity to have enduring relationships with other people (OR 0.878, 95% CI 0.797–0.966), and lower capability to cooperate with others (OR 0.933, 95%CI 0.888–0.98). On the other hand, except for self-respect, other elements of the Identity Integration domain (enjoyment, purposefulness, stable self-image, and self-reflexive functioning), when more functional, increased the risk of HCV infection.ConclusionsOur study demonstrates that opiate addicts on opioid substitution treatment have a higher risk of HCV infection if their personality is dysfunctional, especially in the aspects of self-respect, enduring relationships, and cooperativity. The risk is even higher in addicts who have an established diagnosis of any kind of personality disorder. |
| first_indexed | 2024-04-12T04:55:40Z |
| format | Article |
| id | doaj.art-5d676826ce2843e080f74de4c4d2bef4 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-04-12T04:55:40Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-5d676826ce2843e080f74de4c4d2bef42022-12-22T03:47:09ZengFrontiers Media S.A.Frontiers in Public Health2296-25652022-09-011010.3389/fpubh.2022.10094131009413Personality dysfunction in opiate addicts on opioid substitution treatment and the risk of HCV infectionSiniša Skočibušić0Nera Zivlak-Radulović1Mevludin Hasanović2Hassan Awad3Dragana Karan-Križanac4Nermana Mehić-Basara5Tomislav Rukavina6Clinic for Infectious Diseases, University Clinical Hospital Mostar and Center for Prevention and Outpatient Treatment of Addiction, Mostar, Bosnia and HerzegovinaClinic for Psychiatry, University Clinical Center of Republic of Srpska, Banja Luka, Bosnia and HerzegovinaClinic for Psychiatry, University Clinical Center Tuzla, Tuzla, Bosnia and HerzegovinaPublic Institute for Addiction Disorders of Canton Zenica-Doboj, Zenica, Bosnia and HerzegovinaDepartment of Pathology, Cytology and Forensic Medicine, University Clinical Hospital Mostar, Mostar, Bosnia and HerzegovinaPublic Institute for Addiction Disorders of Canton Sarajevo, Sarajevo, Bosnia and HerzegovinaFaculty of Medicine, University of Rijeka and Teaching Institute of Public Health, Rijeka, CroatiaBackgroundImpulsivity, affective instability, and neglect of oneself and other people's safety as symptoms of personality dysfunction are associated with risky behaviors regarding the transmission of infectious diseases either sexually or by intravenous drug abuse.ObjectiveThe aim of this study was to analyze the association between hepatitis C virus (HCV) infection and personality dysfunction in opiate addicts on opioid substitution treatment.MethodsThis was a cross-sectional, observational investigation of patients over 18 years of age who were actively participating in opioid substitution treatment at five centers in Bosnia and Herzegovina. The occurrence of HCV infection was the primary study outcome, and personality functioning, the main independent variable, was assessed using the Severity Indices of Personality Problems (SIPP−118) questionnaire. The association between scores of personality functioning domains items and HCV infection status was determined by binary logistic regression analysis.ResultsPatients on opioid substitution therapy with HCV infection more frequently had personality disorders (OR 2.168, 95% CI 1.161–4.05) and were treated longer than patients without HCV infection (OR 1.076, 95% CI 1.015–1.14). HCV infection was associated with lower self-respect (OR 0.946, 95% CI 0.906–0.988), decreased capacity to have enduring relationships with other people (OR 0.878, 95% CI 0.797–0.966), and lower capability to cooperate with others (OR 0.933, 95%CI 0.888–0.98). On the other hand, except for self-respect, other elements of the Identity Integration domain (enjoyment, purposefulness, stable self-image, and self-reflexive functioning), when more functional, increased the risk of HCV infection.ConclusionsOur study demonstrates that opiate addicts on opioid substitution treatment have a higher risk of HCV infection if their personality is dysfunctional, especially in the aspects of self-respect, enduring relationships, and cooperativity. The risk is even higher in addicts who have an established diagnosis of any kind of personality disorder.https://www.frontiersin.org/articles/10.3389/fpubh.2022.1009413/fullopiate substitution treatmenthepatitis Cchronicrisk factorspersonality disordersopiate addicts |
| spellingShingle | Siniša Skočibušić Nera Zivlak-Radulović Mevludin Hasanović Hassan Awad Dragana Karan-Križanac Nermana Mehić-Basara Tomislav Rukavina Personality dysfunction in opiate addicts on opioid substitution treatment and the risk of HCV infection Frontiers in Public Health opiate substitution treatment hepatitis C chronic risk factors personality disorders opiate addicts |
| title | Personality dysfunction in opiate addicts on opioid substitution treatment and the risk of HCV infection |
| title_full | Personality dysfunction in opiate addicts on opioid substitution treatment and the risk of HCV infection |
| title_fullStr | Personality dysfunction in opiate addicts on opioid substitution treatment and the risk of HCV infection |
| title_full_unstemmed | Personality dysfunction in opiate addicts on opioid substitution treatment and the risk of HCV infection |
| title_short | Personality dysfunction in opiate addicts on opioid substitution treatment and the risk of HCV infection |
| title_sort | personality dysfunction in opiate addicts on opioid substitution treatment and the risk of hcv infection |
| topic | opiate substitution treatment hepatitis C chronic risk factors personality disorders opiate addicts |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2022.1009413/full |
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