LL37 Inhibits Aspergillus fumigatus Infection via Directly Binding to the Fungus and Preventing Excessive Inflammation

The incidence of Aspergillus fumigatus infection and the rate of resistance to antifungal drugs have sharply increased in recent years. LL37 has been reported as a host defense peptide with broad-spectrum antibacterial activities. However, the role of LL37 during A. fumigatus infection remains uncle...

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Main Authors: Xiao-Li Luo, Jian-Xiong Li, Hua-Rong Huang, Jie-Lin Duan, Ruo-Xuan Dai, Ru-Jia Tao, Ling Yang, Jia-yun Hou, Xin-Ming Jia, Jin-Fu Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00283/full