Changes in Locomotor Activity and Oxidative Stress-Related Factors after the Administration of an Amino Acid Mixture by Generation and Age

Changes in Locomotor Activity and Oxidative Stress-Related Factors after the Administration of an Amino Acid Mixture by Generation and Age

Amino acids, as nutrients, are expected to improve sleep disorders. This study aimed to evaluate the generation- and age-dependent sleep-improving effects of γ-aminobutyric acid (GABA) and 5-hydroxytryptophan (5-HTP) coadministration. The differentially expressed genes and generation-related behavio...

Full description

Bibliographic Details
Main Authors:	Yejin Ahn, Ki-Bae Hong, Suhyeon Kim, Hyung Joo Suh, Kyungae Jo
Format:	Article
Language:	English
Published:	MDPI AG 2021-09-01
Series:	International Journal of Molecular Sciences
Subjects:	γ-aminobutyric acid 5-hydroxytryptophan sleep reactive oxygen species generation age
Online Access:	https://www.mdpi.com/1422-0067/22/18/9822

Similar Items

Fermented Gamma Aminobutyric Acid Improves Sleep Behaviors in Fruit Flies and Rodent Models
by: A-Hyun Jeong, et al.
Published: (2021-03-01)

Characterization of GABA-Transaminase Gene from Mulberry (<i>Morus multicaulis</i>) and Its Role in Salt Stress Tolerance
by: Mengru Zhang, et al.
Published: (2022-03-01)

Exogenous γ-Aminobutyric Acid Delays Chilling Injury of Harvested Kiwifruit and Relates with Reactive Oxygen Species Metabolism
by: XIA Minghui, ZHANG Shen, ZHAO Yunfeng, WANG Ying, HE Fan, CHEN Fahe, LIN Yifen, CHEN Fuquan
Published: (2023-10-01)

Combination of Cysteine and Glutathione Prevents Ethanol-Induced Hangover and Liver Damage by Modulation of Nrf2 Signaling in HepG2 Cells and Mice
by: Hyeongyeong Kim, et al.
Published: (2023-10-01)

Participation of γ-aminobutyric acid in cell signaling processes and plant adaptation to abiotic stressors
by: Yuriy E. Kolupaev, et al.
Published: (2024-03-01)

Polyamines and abiotic stress in plants: A complex relationship
by: Rakesh eMinocha, et al.
Published: (2014-05-01)

Synthesis of γ-Aminobutyric Acid-Modified Chitooligosaccharide Derivative and Enhancing Salt Resistance of Wheat Seedlings
by: Wenyun Wang, et al.
Published: (2022-05-01)

Morinda officinalis oligosaccharides increase serotonin in the brain and ameliorate depression via promoting 5-hydroxytryptophan production in the gut microbiota
by: Zheng-Wei Zhang, et al.
Published: (2022-08-01)

Integrating animal experiments, mass spectrometry and network-based approach to reveal the sleep-improving effects of Ziziphi Spinosae Semen and γ-aminobutyric acid mixture
by: Airong Ren, et al.
Published: (2023-08-01)

The use of deuterium-labeled gamma-aminobutyric (D6-GABA) to study uptake, translocation, and metabolism of exogenous GABA in plants
by: Faraj Hijaz, et al.
Published: (2020-02-01)

Metallothionein 3 Inhibits 3T3-L1 Adipocyte Differentiation via Reduction of Reactive Oxygen Species
by: Yuankuan Li, et al.
Published: (2023-03-01)

Muscimol Directly Activates the TREK-2 Channel Expressed in GABAergic Neurons through Its N-Terminus
by: Eun-Jin Kim, et al.
Published: (2021-08-01)

Effects of Green Lettuce Leaf Extract on Sleep Disturbance Control in Oxidative Stress-Induced Invertebrate and Vertebrate Models
by: Kyungae Jo, et al.
Published: (2021-06-01)

Intravenous infusion of 5-hydroxytryptophan to mid-lactation Holstein cows transiently affects milk production and circulating amino acid concentrations
by: Virginia L. Pszczolkowski, et al.
Published: (2024-05-01)

Sleep-Enhancing Effect of Water Extract from Jujube (<i>Zizyphus jujuba</i> Mill.) Seeds Fermented by <i>Lactobacillus brevis</i> L32
by: Gi Yeon Bae, et al.
Published: (2023-07-01)

Effects of Germination on the Content of Amino Acids and Anti-nutritional Factors of Sorghum Grain
by: Jun ZHANG, et al.
Published: (2022-01-01)

5‐Hydroxytryptophan toxicity successfully treated by haemodialysis in a dog
by: Diana Victoria Arbona, et al.
Published: (2023-11-01)

Quercetin-3-<i>O</i>-glucuronide in the Ethanol Extract of Lotus Leaf (<i>Nelumbo nucifera</i>) Enhances Sleep Quantity and Quality in a Rodent Model via a GABAergic Mechanism
by: Singeun Kim, et al.
Published: (2021-05-01)

Exogenous γ-aminobutyric acid strengthens phenylpropanoid and nitrogen metabolism to enhance the contents of flavonoids, amino acids, and the derivatives in edamame
by: Gaobo Yu, et al.
Published: (2022-12-01)

Ameliorative Effect and Mechanism of Cerasus humilis (Bge.) Sok on Insomnia in Mice
by: FU Rao, LIANG Zhe, WEN Xin, NI Yuanying
Published: (2023-11-01)

HMG-CoA Reductase Inhibitors Suppress Monosodium Urate-Induced NLRP3 Inflammasome Activation through Peroxisome Proliferator-Activated Receptor-γ Activation in THP-1 Cells
by: Seong-Kyu Kim, et al.
Published: (2023-03-01)

γ-aminobutyric acid alleviates LPS-induced acute lung injury in mice through upregulating type B receptors
by: Jing Yang, et al.
Published: (2019-11-01)

1,3-Bis(3-carboxypropyl)-1<i>H</i>-imidazole
by: Mario Martos, et al.
Published: (2022-11-01)

The γ-Aminobutyric Acid (GABA) Synthesis Gene Regulates the Resistance to Water Core-Induced Hypoxia Stress for Pear Fruits
by: Xiao Liu, et al.
Published: (2023-04-01)

Watercore Pear Fruit Respiration Changed and Accumulated γ-Aminobutyric Acid (GABA) in Response to Inner Hypoxia Stress
by: Xiao Liu, et al.
Published: (2022-05-01)

Novel ultrashort-acting benzodiazepine remimazolam lowers shivering threshold in rabbits
by: Kenji Muroya, et al.
Published: (2022-10-01)

Effect of components in homogeneous extraction suspensions of pea and sweet buckwheat on γ-aminobutyric acid synthesis
by: Yulong Huang, et al.
Published: (2019-08-01)

Different characteristics of 40 kinds of free amino acids and 5-amino levulinic acid between wines and sakes (Japanese rice wines)
by: Tohru Kimura
Published: (2024-12-01)

An in vitro analysis of an innovative standardized phospholipid carrier-based Melissa officinalis L. extract as a potential neuromodulator for emotional distress and related conditions
by: Mehtap Kara, et al.
Published: (2024-03-01)

Sleep Fragmentation Accelerates Carcinogenesis in a Chemical-Induced Colon Cancer Model
by: Da-Been Lee, et al.
Published: (2023-02-01)

Sleep-promoting activity of lotus (Nelumbo nucifera) rhizome water extract via GABAA receptors
by: Yejin Ahn, et al.
Published: (2022-12-01)

Optimization Technology of Longshan Millet γ-amino Butyric Acid Enrichment Process by Neural Network Algorithm
by: ZHANG Yi-ming, et al.
Published: (2022-05-01)

Variations of Free Amino Acids during the Germination of Brown Foxtail Millet
by: LIU Jing-ke, et al.
Published: (2022-07-01)

Application of γ-aminobutyric acid improves the postharvest marketability of strawberry by maintaining fruit quality and enhancing antioxidant system
by: Yunting Zhang, et al.
Published: (2024-03-01)

The metabolic reprogramming of γ-aminobutyrate in oral squamous cell carcinoma
by: Shi-Lian Wu, et al.
Published: (2024-04-01)

RETRACTED ARTICLE: Effect of apoptosis in neural stem cells treated with sevoflurane
by: Jianlei Qiu, et al.
Published: (2015-03-01)

Functional characterization of Capsicum chinense vanillin aminotransferase: Detection of vanillylamine-forming activity from vanillin
by: Yasuo Kato, et al.
Published: (2024-07-01)

Dietary γ-Aminobutyric Acid Supplementation Inhibits High-Fat Diet-Induced Hepatic Steatosis via Modulating Gut Microbiota in Broilers
by: Qu Chen, et al.
Published: (2022-06-01)

Mepirapim, a Novel Synthetic Cannabinoid, Induces Addiction-Related Behaviors through Neurochemical Maladaptation in the Brain of Rodents
by: Kwang-Hyun Hur, et al.
Published: (2022-06-01)

Effect of ultrasound and microwave pretreatment on sprouting, GABA, bioactive compounds, and other physicochemical properties of sorghum
by: Anagha Deore, et al.
Published: (2023-06-01)