5-Methyl-1-phenyl-3-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridin-6(3<i>H</i>)-one

5-Methyl-1-phenyl-3-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridin-6(3<i>H</i>)-one

A chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridinone derivative <b>3</b> bearing thieno[2,3-<i>d</i>]pyrimidine moiety, 5-methyl-1-phenyl-3-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b<...

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Մատենագիտական մանրամասներ
Հիմնական հեղինակներ: Xuelian Yin, Yang-Heon Song
Ձևաչափ: Հոդված
Լեզու:English
Հրապարակվել է: MDPI AG 2022-10-01
Շարք:Molbank
Խորագրեր:
coumarin
pyrazolo[3,4-<i>b</i>]pyridine
thieno[2,3-<i>d</i>]pyrimidine
FeCl<sub>3</sub>-SiO<sub>2</sub>
Առցանց հասանելիություն:https://www.mdpi.com/1422-8599/2022/4/M1469
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author Xuelian Yin
Yang-Heon Song
author_facet Xuelian Yin
Yang-Heon Song
author_sort Xuelian Yin
collection DOAJ
description A chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridinone derivative <b>3</b> bearing thieno[2,3-<i>d</i>]pyrimidine moiety, 5-methyl-1-phenyl-3-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridin-6(3<i>H</i>)-one, was efficiently prepared in 75% yield by the reaction of 3-phenyl-1-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)-1<i>H</i>-pyrazol-5-amine <b>1</b> with 3-acetyl-2<i>H</i>-chromen-2-one <b>2</b> in the presence of FeCl<sub>3</sub>-SiO<sub>2</sub> as a catalyst in refluxing ethanol for 6 h. The structure of the new synthesized compound was characterized by <sup>1</sup>H-, <sup>13</sup>C- NMR, IR spectroscopy, mass-spectrometry, and elemental analysis.
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spelling doaj.art-5d72c04aca384765a7466ec32874df4c2023-11-24T16:53:48ZengMDPI AGMolbank1422-85992022-10-0120224M146910.3390/M14695-Methyl-1-phenyl-3-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridin-6(3<i>H</i>)-oneXuelian Yin0Yang-Heon Song1Department of Chemistry, Mokwon University, Daejeon 35349, KoreaDepartment of Chemistry, Mokwon University, Daejeon 35349, KoreaA chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridinone derivative <b>3</b> bearing thieno[2,3-<i>d</i>]pyrimidine moiety, 5-methyl-1-phenyl-3-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridin-6(3<i>H</i>)-one, was efficiently prepared in 75% yield by the reaction of 3-phenyl-1-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)-1<i>H</i>-pyrazol-5-amine <b>1</b> with 3-acetyl-2<i>H</i>-chromen-2-one <b>2</b> in the presence of FeCl<sub>3</sub>-SiO<sub>2</sub> as a catalyst in refluxing ethanol for 6 h. The structure of the new synthesized compound was characterized by <sup>1</sup>H-, <sup>13</sup>C- NMR, IR spectroscopy, mass-spectrometry, and elemental analysis.https://www.mdpi.com/1422-8599/2022/4/M1469coumarinpyrazolo[3,4-<i>b</i>]pyridinethieno[2,3-<i>d</i>]pyrimidineFeCl<sub>3</sub>-SiO<sub>2</sub>
spellingShingle Xuelian Yin
Yang-Heon Song
5-Methyl-1-phenyl-3-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridin-6(3<i>H</i>)-one
Molbank
coumarin
pyrazolo[3,4-<i>b</i>]pyridine
thieno[2,3-<i>d</i>]pyrimidine
FeCl<sub>3</sub>-SiO<sub>2</sub>
title 5-Methyl-1-phenyl-3-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridin-6(3<i>H</i>)-one
title_full 5-Methyl-1-phenyl-3-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridin-6(3<i>H</i>)-one
title_fullStr 5-Methyl-1-phenyl-3-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridin-6(3<i>H</i>)-one
title_full_unstemmed 5-Methyl-1-phenyl-3-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridin-6(3<i>H</i>)-one
title_short 5-Methyl-1-phenyl-3-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridin-6(3<i>H</i>)-one
title_sort 5 methyl 1 phenyl 3 thieno 2 3 i d i pyrimidin 4 yl chromeno 4 3 i d i pyrazolo 3 4 i b i pyridin 6 3 i h i one
topic coumarin
pyrazolo[3,4-<i>b</i>]pyridine
thieno[2,3-<i>d</i>]pyrimidine
FeCl<sub>3</sub>-SiO<sub>2</sub>
url https://www.mdpi.com/1422-8599/2022/4/M1469
work_keys_str_mv AT xuelianyin 5methyl1phenyl3thieno23idipyrimidin4ylchromeno43idipyrazolo34ibipyridin63ihione
AT yangheonsong 5methyl1phenyl3thieno23idipyrimidin4ylchromeno43idipyrazolo34ibipyridin63ihione

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