A nanoluciferase SFTSV for rapid screening antivirals and real-time visualization of virus infection in miceResearch in context

A nanoluciferase SFTSV for rapid screening antivirals and real-time visualization of virus infection in miceResearch in context

Summary: Background: Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne pathogen that causes severe hemorrhagic fever in humans, but no FDA-approved specific antivirals or vaccines are available to treat or prevent SFTS. Methods: The plasmids construction and transf...

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Bibliografiske detaljer
Main Authors: Huan Xu, Xiaoqin Jian, Yuxi Wen, Mengwei Xu, Runming Jin, Xiaoyan Wu, Fen Zhou, Junyuan Cao, Gengfu Xiao, Ke Peng, Yuanchao Xie, Hongbo Chen, Leike Zhang
Format: Article
Sprog:English
Udgivet: Elsevier 2024-01-01
Serier:EBioMedicine
Fag:
Severe fever with thrombocytopenia syndrome virus
Nanoluciferase reporter gene
High-throughput drug screening
In vivo bioluminescence imaging
4′-fluorouridine
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