Transcranial direct current stimulation for the treatment of post-stroke depression: A systematic review
BackgroundPost-stroke depression (PSD) is not only a frequent neuropsychiatric manifestation secondary to stroke but is also associated with disability, poor rehabilitation outcomes, sleep disorders, cognitive impairment, and increased mortality. Transcranial direct current stimulation (tDCS), a pri...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.955209/full |
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| author | Wenjian Hao Wenjian Hao Yong Liu Yong Liu Yuling Gao Xiaoyang Gong Yi Ning |
| author_facet | Wenjian Hao Wenjian Hao Yong Liu Yong Liu Yuling Gao Xiaoyang Gong Yi Ning |
| author_sort | Wenjian Hao |
| collection | DOAJ |
| description | BackgroundPost-stroke depression (PSD) is not only a frequent neuropsychiatric manifestation secondary to stroke but is also associated with disability, poor rehabilitation outcomes, sleep disorders, cognitive impairment, and increased mortality. Transcranial direct current stimulation (tDCS), a primary modality of non-invasive brain stimulation (NIBS), has shown promising clinical results in the rehabilitation of patients with PSD recently. The primary aim of this systematic review is to assess the effects of tDCS on PSD.MethodsPubMed and Cochrane databases were used for paper identification up to May 2022. Only English language studies and published data were taken into consideration. The methodological quality of selected studies was assessed according to the modified Sackett Scale, based on Physiotherapy Evidence Database (PEDro) scores.ResultsSix experimental studies were included for the PSD treatment of tDCS and all of them reported that, following the intervention of tDCS, the experimental group shows a statistically significant decrease in the depression level in accordance with different assessment scales.ConclusionThis article simply aims at providing a comprehensive overview of the raw data reported in this field to date. Based on the current evidence, tDCS presents promising results for the treatment of PSD. Moreover, tDCS is also effective in PSD patients with aphasia or CPSP. However, an optimal stimulation protocol is needed to formulate. Thus, the development of robustly controlled, randomized, and high-quality clinical trials to further assess the utility of tDCS as a therapeutic tool for the treatment of PSD survivors is encouraged.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023322076, identifier: CRD42023322076. |
| first_indexed | 2024-04-10T21:29:27Z |
| format | Article |
| id | doaj.art-5d7534af858849fe9e1e80b53ef2e49b |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-10T21:29:27Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-5d7534af858849fe9e1e80b53ef2e49b2023-01-19T14:44:12ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-01-011310.3389/fneur.2022.955209955209Transcranial direct current stimulation for the treatment of post-stroke depression: A systematic reviewWenjian Hao0Wenjian Hao1Yong Liu2Yong Liu3Yuling Gao4Xiaoyang Gong5Yi Ning6Department of Rehabilitation Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, ChinaInstitute (College) of Integrative Medicine, Dalian Medical University, Dalian, ChinaDepartment of Rehabilitation Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, ChinaInstitute (College) of Integrative Medicine, Dalian Medical University, Dalian, ChinaDepartment of Rehabilitation Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, ChinaDepartment of Rehabilitation Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, ChinaInstitute (College) of Integrative Medicine, Dalian Medical University, Dalian, ChinaBackgroundPost-stroke depression (PSD) is not only a frequent neuropsychiatric manifestation secondary to stroke but is also associated with disability, poor rehabilitation outcomes, sleep disorders, cognitive impairment, and increased mortality. Transcranial direct current stimulation (tDCS), a primary modality of non-invasive brain stimulation (NIBS), has shown promising clinical results in the rehabilitation of patients with PSD recently. The primary aim of this systematic review is to assess the effects of tDCS on PSD.MethodsPubMed and Cochrane databases were used for paper identification up to May 2022. Only English language studies and published data were taken into consideration. The methodological quality of selected studies was assessed according to the modified Sackett Scale, based on Physiotherapy Evidence Database (PEDro) scores.ResultsSix experimental studies were included for the PSD treatment of tDCS and all of them reported that, following the intervention of tDCS, the experimental group shows a statistically significant decrease in the depression level in accordance with different assessment scales.ConclusionThis article simply aims at providing a comprehensive overview of the raw data reported in this field to date. Based on the current evidence, tDCS presents promising results for the treatment of PSD. Moreover, tDCS is also effective in PSD patients with aphasia or CPSP. However, an optimal stimulation protocol is needed to formulate. Thus, the development of robustly controlled, randomized, and high-quality clinical trials to further assess the utility of tDCS as a therapeutic tool for the treatment of PSD survivors is encouraged.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023322076, identifier: CRD42023322076.https://www.frontiersin.org/articles/10.3389/fneur.2022.955209/fullstrokedepressionmechanismtranscranial direct current stimulationpost-stroke depression (PSD) |
| spellingShingle | Wenjian Hao Wenjian Hao Yong Liu Yong Liu Yuling Gao Xiaoyang Gong Yi Ning Transcranial direct current stimulation for the treatment of post-stroke depression: A systematic review Frontiers in Neurology stroke depression mechanism transcranial direct current stimulation post-stroke depression (PSD) |
| title | Transcranial direct current stimulation for the treatment of post-stroke depression: A systematic review |
| title_full | Transcranial direct current stimulation for the treatment of post-stroke depression: A systematic review |
| title_fullStr | Transcranial direct current stimulation for the treatment of post-stroke depression: A systematic review |
| title_full_unstemmed | Transcranial direct current stimulation for the treatment of post-stroke depression: A systematic review |
| title_short | Transcranial direct current stimulation for the treatment of post-stroke depression: A systematic review |
| title_sort | transcranial direct current stimulation for the treatment of post stroke depression a systematic review |
| topic | stroke depression mechanism transcranial direct current stimulation post-stroke depression (PSD) |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.955209/full |
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