Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome.
Therapeutic modulation of protein interactions is challenging, but short linear motifs (SLiMs) represent potential targets. Focal adhesions play a central role in adhesion by linking cells to the extracellular matrix. Integrins are central to this process, and many other intracellular proteins are c...
Main Authors: | Kevin T O'Brien, Kalyan Golla, Tilen Kranjc, Darragh O'Donovan, Seamus Allen, Patricia Maguire, Jeremy C Simpson, David O'Connell, Niamh Moran, Denis C Shields |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0210337 |
Similar Items
-
Characterisation of a nucleo-adhesome
by: Adam Byron, et al.
Published: (2022-06-01) -
Identification of adhesomes in embryonic stem cells
by: Teh, Velda Yan Qin
Published: (2017) -
The Adhesome Network: Key Components Shaping the Tumour Stroma
by: Pinelopi A. Nikolopoulou, et al.
Published: (2021-01-01) -
Dissecting the Inorganic Nanoparticle-Driven Interferences on Adhesome Dynamics
by: Vladimir Mulens-Arias
Published: (2021-09-01) -
Peptides derived from cadherin juxtamembrane region inhibit platelet function
by: Kalyan Golla, et al.
Published: (2018-01-01)