Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia
The prevalence of genotypes and alleles of polymorphic marker S1 /S2 Apolipoprotein C3 in healthy adolescent Caucasians (Russians) living in Eastern Siberia was studied. Material for research was the DNA extracted from the venous blood; genotype was determined by PCR-RFLP for each sample. In the stu...
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| Format: | Article |
| Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2014-09-01
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| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/1822 |
| _version_ | 1797237481968500736 |
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| author | O. V. Kalyuzhnaya T. A. Bairova V. V. Dolgikh S. I. Kolesnikov |
| author_facet | O. V. Kalyuzhnaya T. A. Bairova V. V. Dolgikh S. I. Kolesnikov |
| author_sort | O. V. Kalyuzhnaya |
| collection | DOAJ |
| description | The prevalence of genotypes and alleles of polymorphic marker S1 /S2 Apolipoprotein C3 in healthy adolescent Caucasians (Russians) living in Eastern Siberia was studied. Material for research was the DNA extracted from the venous blood; genotype was determined by PCR-RFLP for each sample. In the studied sample in 88.9 % of cases genotype S1/ S1 was detected, genotype S1/S2 was found in 8.6 %, S2/S2 - in 2.5 %. The share of S2 allele was 6.8 %, which is not significantly different from the previously studied Caucasoid populations. |
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| format | Article |
| id | doaj.art-5d78fba6b5db47cda2d898e34c7febd9 |
| institution | Directory Open Access Journal |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| last_indexed | 2024-04-24T17:20:27Z |
| publishDate | 2014-09-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj.art-5d78fba6b5db47cda2d898e34c7febd92024-03-28T07:49:13ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962014-09-010595971768Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern SiberiaO. V. Kalyuzhnaya0T. A. Bairova1V. V. Dolgikh2S. I. Kolesnikov3Scientific Center for Family Health and Human Reproduction ProblemsScientific Center for Family Health and Human Reproduction ProblemsScientific Center for Family Health and Human Reproduction ProblemsRASThe prevalence of genotypes and alleles of polymorphic marker S1 /S2 Apolipoprotein C3 in healthy adolescent Caucasians (Russians) living in Eastern Siberia was studied. Material for research was the DNA extracted from the venous blood; genotype was determined by PCR-RFLP for each sample. In the studied sample in 88.9 % of cases genotype S1/ S1 was detected, genotype S1/S2 was found in 8.6 %, S2/S2 - in 2.5 %. The share of S2 allele was 6.8 %, which is not significantly different from the previously studied Caucasoid populations.https://www.actabiomedica.ru/jour/article/view/1822s1/s2apolipoprotein c3s1/s2allelegenotype |
| spellingShingle | O. V. Kalyuzhnaya T. A. Bairova V. V. Dolgikh S. I. Kolesnikov Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia Acta Biomedica Scientifica s1/s2 apolipoprotein c3 s1/s2 allele genotype |
| title | Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia |
| title_full | Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia |
| title_fullStr | Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia |
| title_full_unstemmed | Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia |
| title_short | Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia |
| title_sort | study of apolipoprotein c3 s1 s2 c3238g rs5128 polymorphism in caucasian population of eastern siberia |
| topic | s1/s2 apolipoprotein c3 s1/s2 allele genotype |
| url | https://www.actabiomedica.ru/jour/article/view/1822 |
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