Valepotriates From the Roots and Rhizomes of Valeriana jatamansi Jones as Novel N-Type Calcium Channel Antagonists

Valepotriates From the Roots and Rhizomes of Valeriana jatamansi Jones as Novel N-Type Calcium Channel Antagonists

The roots and rhizomes of Valeriana jatamansi have long been used as folk medicine in Asia and usually named as “Zhizhuxiang” in Chinese for the treatment of abdominal distention and pain. However, its active ingredients and molecular targets for treatment of abdominal pain remain unrevealed. Inhibi...

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Bibliographic Details
Main Authors: Fa-Wu Dong, He-Hai Jiang, Liu Yang, Ye Gong, Cheng-Ting Zi, Dan Yang, Chen-Jun Ye, Huan Li, Jian Yang, Yin Nian, Jun Zhou, Jiang-Miao Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Pharmacology
Subjects:
Valeriana jatamansi
iridoid
abdominal distention and pain
N-type voltage-gated calcium channels
Cav2.2
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00885/full

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