Molecular-genetic mechanisms of the signal cascade RAS-RAF-MEK-ERK associated with the development of the tumor process and the purpose of targeted drugs for colorectal cancer

Molecular-genetic mechanisms of the signal cascade RAS-RAF-MEK-ERK associated with the development of the tumor process and the purpose of targeted drugs for colorectal cancer

Colorectal cancer occupies one of the leading positions in the world in the structure of cancer incidence. The vital processes of cancer cells largely depend on the production of growth factors and their receptors. One of these is epidermal growth factor (EGFR), which is a tyrosine kinase receptor f...

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Bibliographic Details
Main Authors:	A. N. Toropovsky, O. N. Pavlova, D. A. Viktorov, A. G. Nikitin
Format:	Article
Language:	Russian
Published:	Private institution educational organization of higher education "Medical University "ReaViz" 2021-08-01
Series:	Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Subjects:	colorectal cancer colon and rectal cancer metastatic colorectal cancer egfr hras kras nras rras ras-raf-mek-erk signal stage
Online Access:	https://vestnik.reaviz.ru/jour/article/view/279

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