A lipid-binding protein mediates rhoptry discharge and invasion in Plasmodium falciparum and Toxoplasma gondii parasites

A lipid-binding protein mediates rhoptry discharge and invasion in Plasmodium falciparum and Toxoplasma gondii parasites

Plasmodium and Toxoplasma parasites rely on rhoptry exocytosis for invasion, but the underlying mechanism is not known. Here, Suarez et al. characterize rhoptry apical surface proteins (RASP) that localize to the rhoptry cap and bind charged lipids, and are essential for rhoptry secretion and invasi...

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Bibliographic Details
Main Authors: Catherine Suarez, Gaëlle Lentini, Raghavendran Ramaswamy, Marjorie Maynadier, Eleonora Aquilini, Laurence Berry-Sterkers, Michael Cipriano, Allan L. Chen, Peter Bradley, Boris Striepen, Martin J. Boulanger, Maryse Lebrun
Format: Article
Language:English
Published: Nature Portfolio 2019-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11979-z

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