Allogeneic ADSCs Induce the Production of Alloreactive Memory-CD8 T Cells through HLA-ABC Antigens

Allogeneic ADSCs Induce the Production of Alloreactive Memory-CD8 T Cells through HLA-ABC Antigens

We investigated the immunogenicity of allogeneic human adipose-derived mesenchymal stem cells (ADSCs) through the production of alloreactive-CD8 T and -memory CD8 T cells, based on their human leukocyte antigen (HLA) expression. In surface antigen analysis, ADSCs do not express co-stimulatory molecu...

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Bibliographic Details
Main Authors:	Sung-Ho Chang, Hyun Je Kim, Chung-Gyu Park
Format:	Article
Language:	English
Published:	MDPI AG 2020-05-01
Series:	Cells
Subjects:	adipose-derived mesenchymal stem cells (ADSCs) direct pathway alloreactive memory CD8 T cells human leukocyte antigen (HLA) immunogenicity
Online Access:	https://www.mdpi.com/2073-4409/9/5/1246

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