Use of mesenchymal stem cell therapy in COVID-19 related strokes

Coronavirus disease 2019 (COVID-19) has affected a broad demographics, eliciting a more significant effect on specific groups such as males, African Americans, and Hispanic minorities. Treatment of COVID-19 often requires antiviral drugs or monoclonal antibodies. However, immunotherapies such as mes...

Full description

Bibliographic Details
Main Authors: Mahika Rawat, Chiao Ng, Emaad Khan, Rayyan A Shah, Suha Ashfaq, Ghaith A Bahader, Zahoor A Shah
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=9;spage=1881;epage=1883;aulast=Rawat
_version_ 1797866431823478784
author Mahika Rawat
Chiao Ng
Emaad Khan
Rayyan A Shah
Suha Ashfaq
Ghaith A Bahader
Zahoor A Shah
author_facet Mahika Rawat
Chiao Ng
Emaad Khan
Rayyan A Shah
Suha Ashfaq
Ghaith A Bahader
Zahoor A Shah
author_sort Mahika Rawat
collection DOAJ
description Coronavirus disease 2019 (COVID-19) has affected a broad demographics, eliciting a more significant effect on specific groups such as males, African Americans, and Hispanic minorities. Treatment of COVID-19 often requires antiviral drugs or monoclonal antibodies. However, immunotherapies such as mesenchymal stem cells and mesenchymal stem cells-derived exosomal vesicles should be evaluated as treatment options for COVID-19. Mesenchymal stem cell therapy offers regenerative, anti-inflammatory, and immunomodulatory properties that can speed up the recovery from COVID-19. Mesenchymal stem cell therapy can also benefit COVID-19 patients who suffer from strokes, as COVID-19 increases the risk of strokes due to increased cytokines and clotting factors. Most stroke cases that occur in COVID-19 patients are ischemic strokes. Therefore, with the help of mesenchymal stem cell therapy and mesenchymal stem cells-derived exosomes, COVID-19-induced stroke patients might benefit from dual-ended treatment. The objective of this review was to discuss COVID-19 and stroke incidence and the available treatment options.
first_indexed 2024-04-09T23:24:04Z
format Article
id doaj.art-5d85cfc9507246b6bc53bce2991c2c70
institution Directory Open Access Journal
issn 1673-5374
language English
last_indexed 2024-04-09T23:24:04Z
publishDate 2023-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Neural Regeneration Research
spelling doaj.art-5d85cfc9507246b6bc53bce2991c2c702023-03-21T11:23:56ZengWolters Kluwer Medknow PublicationsNeural Regeneration Research1673-53742023-01-011891881188310.4103/1673-5374.367927Use of mesenchymal stem cell therapy in COVID-19 related strokesMahika RawatChiao NgEmaad KhanRayyan A ShahSuha AshfaqGhaith A BahaderZahoor A ShahCoronavirus disease 2019 (COVID-19) has affected a broad demographics, eliciting a more significant effect on specific groups such as males, African Americans, and Hispanic minorities. Treatment of COVID-19 often requires antiviral drugs or monoclonal antibodies. However, immunotherapies such as mesenchymal stem cells and mesenchymal stem cells-derived exosomal vesicles should be evaluated as treatment options for COVID-19. Mesenchymal stem cell therapy offers regenerative, anti-inflammatory, and immunomodulatory properties that can speed up the recovery from COVID-19. Mesenchymal stem cell therapy can also benefit COVID-19 patients who suffer from strokes, as COVID-19 increases the risk of strokes due to increased cytokines and clotting factors. Most stroke cases that occur in COVID-19 patients are ischemic strokes. Therefore, with the help of mesenchymal stem cell therapy and mesenchymal stem cells-derived exosomes, COVID-19-induced stroke patients might benefit from dual-ended treatment. The objective of this review was to discuss COVID-19 and stroke incidence and the available treatment options.http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=9;spage=1881;epage=1883;aulast=Rawatcovid-19; cytokines; immunotherapy; interleukin-7; mesenchymal stem cells; neuroinflammation; sex differences; stroke
spellingShingle Mahika Rawat
Chiao Ng
Emaad Khan
Rayyan A Shah
Suha Ashfaq
Ghaith A Bahader
Zahoor A Shah
Use of mesenchymal stem cell therapy in COVID-19 related strokes
Neural Regeneration Research
covid-19; cytokines; immunotherapy; interleukin-7; mesenchymal stem cells; neuroinflammation; sex differences; stroke
title Use of mesenchymal stem cell therapy in COVID-19 related strokes
title_full Use of mesenchymal stem cell therapy in COVID-19 related strokes
title_fullStr Use of mesenchymal stem cell therapy in COVID-19 related strokes
title_full_unstemmed Use of mesenchymal stem cell therapy in COVID-19 related strokes
title_short Use of mesenchymal stem cell therapy in COVID-19 related strokes
title_sort use of mesenchymal stem cell therapy in covid 19 related strokes
topic covid-19; cytokines; immunotherapy; interleukin-7; mesenchymal stem cells; neuroinflammation; sex differences; stroke
url http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=9;spage=1881;epage=1883;aulast=Rawat
work_keys_str_mv AT mahikarawat useofmesenchymalstemcelltherapyincovid19relatedstrokes
AT chiaong useofmesenchymalstemcelltherapyincovid19relatedstrokes
AT emaadkhan useofmesenchymalstemcelltherapyincovid19relatedstrokes
AT rayyanashah useofmesenchymalstemcelltherapyincovid19relatedstrokes
AT suhaashfaq useofmesenchymalstemcelltherapyincovid19relatedstrokes
AT ghaithabahader useofmesenchymalstemcelltherapyincovid19relatedstrokes
AT zahoorashah useofmesenchymalstemcelltherapyincovid19relatedstrokes