Central mucoepidermoid carcinoma in mandible: Case report of a clear cell variant with immunohistochemistry analysis

Mucoepidermoid carcinoma (MEC) is the most common malignancy of the salivary glands that are extremely infrequent in the jaws and is termed central or Intraosseous mucoepidermoid carcinoma. Central mucoepidermoid carcinoma (CMEC) is known to affect the middle age group and has a slight female predil...

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Main Authors: Massillamani Francis, Beshia Arnold, Santana B Natarajan, Deivanayagi Muthusamy
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Indian Academy of Oral Medicine and Radiology
Subjects:
Online Access:http://www.jiaomr.in/article.asp?issn=0972-1363;year=2023;volume=35;issue=1;spage=137;epage=140;aulast=Francis
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author Massillamani Francis
Beshia Arnold
Santana B Natarajan
Deivanayagi Muthusamy
author_facet Massillamani Francis
Beshia Arnold
Santana B Natarajan
Deivanayagi Muthusamy
author_sort Massillamani Francis
collection DOAJ
description Mucoepidermoid carcinoma (MEC) is the most common malignancy of the salivary glands that are extremely infrequent in the jaws and is termed central or Intraosseous mucoepidermoid carcinoma. Central mucoepidermoid carcinoma (CMEC) is known to affect the middle age group and has a slight female predilection. Most of these carcinomas mimic benign odontogenic lesions and very few present as locally aggressive lesions accompanied by clinical signs such as pain, swelling, movement of teeth, and loss of sensation of the inferior alveolar nerve. We are presenting a rare case of central mucoepidermoid carcinoma in a 66-year-old male patient with uniqueness in its arrival at diagnosis. This case substantiates the importance of collaborated histopathological and radiological investigations in the precise diagnosis of such locally aggressive carcinoma with metastatic potential while emphasizing the subsequent surgical reconstruction and its excellent prognosis.
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spelling doaj.art-5d89a6f76f35447f96b9df5878f079de2023-07-21T11:41:25ZengWolters Kluwer Medknow PublicationsJournal of Indian Academy of Oral Medicine and Radiology0972-13632023-01-0135113714010.4103/jiaomr.jiaomr_200_22Central mucoepidermoid carcinoma in mandible: Case report of a clear cell variant with immunohistochemistry analysisMassillamani FrancisBeshia ArnoldSantana B NatarajanDeivanayagi MuthusamyMucoepidermoid carcinoma (MEC) is the most common malignancy of the salivary glands that are extremely infrequent in the jaws and is termed central or Intraosseous mucoepidermoid carcinoma. Central mucoepidermoid carcinoma (CMEC) is known to affect the middle age group and has a slight female predilection. Most of these carcinomas mimic benign odontogenic lesions and very few present as locally aggressive lesions accompanied by clinical signs such as pain, swelling, movement of teeth, and loss of sensation of the inferior alveolar nerve. We are presenting a rare case of central mucoepidermoid carcinoma in a 66-year-old male patient with uniqueness in its arrival at diagnosis. This case substantiates the importance of collaborated histopathological and radiological investigations in the precise diagnosis of such locally aggressive carcinoma with metastatic potential while emphasizing the subsequent surgical reconstruction and its excellent prognosis.http://www.jiaomr.in/article.asp?issn=0972-1363;year=2023;volume=35;issue=1;spage=137;epage=140;aulast=Franciscarcinomaimmunohistochemistrymucoepidermoid
spellingShingle Massillamani Francis
Beshia Arnold
Santana B Natarajan
Deivanayagi Muthusamy
Central mucoepidermoid carcinoma in mandible: Case report of a clear cell variant with immunohistochemistry analysis
Journal of Indian Academy of Oral Medicine and Radiology
carcinoma
immunohistochemistry
mucoepidermoid
title Central mucoepidermoid carcinoma in mandible: Case report of a clear cell variant with immunohistochemistry analysis
title_full Central mucoepidermoid carcinoma in mandible: Case report of a clear cell variant with immunohistochemistry analysis
title_fullStr Central mucoepidermoid carcinoma in mandible: Case report of a clear cell variant with immunohistochemistry analysis
title_full_unstemmed Central mucoepidermoid carcinoma in mandible: Case report of a clear cell variant with immunohistochemistry analysis
title_short Central mucoepidermoid carcinoma in mandible: Case report of a clear cell variant with immunohistochemistry analysis
title_sort central mucoepidermoid carcinoma in mandible case report of a clear cell variant with immunohistochemistry analysis
topic carcinoma
immunohistochemistry
mucoepidermoid
url http://www.jiaomr.in/article.asp?issn=0972-1363;year=2023;volume=35;issue=1;spage=137;epage=140;aulast=Francis
work_keys_str_mv AT massillamanifrancis centralmucoepidermoidcarcinomainmandiblecasereportofaclearcellvariantwithimmunohistochemistryanalysis
AT beshiaarnold centralmucoepidermoidcarcinomainmandiblecasereportofaclearcellvariantwithimmunohistochemistryanalysis
AT santanabnatarajan centralmucoepidermoidcarcinomainmandiblecasereportofaclearcellvariantwithimmunohistochemistryanalysis
AT deivanayagimuthusamy centralmucoepidermoidcarcinomainmandiblecasereportofaclearcellvariantwithimmunohistochemistryanalysis