Balloon Cell Melanoma: Presentation of Four Cases with a Comprehensive Review of the Literature
Background: balloon cell melanoma represents less than 1% of all histological forms of malignant melanoma and represents a diagnostic challenge for the dermatopathologist. Methods: in this paper we present our cases of BCM found in our daily practice from 1 January 2008 to 31 December 2021, and we c...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Dermatopathology |
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| Online Access: | https://www.mdpi.com/2296-3529/9/2/13 |
| _version_ | 1797488378272284672 |
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| author | Gerardo Cazzato Eliano Cascardi Anna Colagrande Antonietta Cimmino Giuseppe Ingravallo Lucia Lospalluti Paolo Romita Aurora Demarco Francesca Arezzo Vera Loizzi Miriam Dellino Irma Trilli Emilio Bellitti Paola Parente Teresa Lettini Caterina Foti Gennaro Cormio Eugenio Maiorano Leonardo Resta |
| author_facet | Gerardo Cazzato Eliano Cascardi Anna Colagrande Antonietta Cimmino Giuseppe Ingravallo Lucia Lospalluti Paolo Romita Aurora Demarco Francesca Arezzo Vera Loizzi Miriam Dellino Irma Trilli Emilio Bellitti Paola Parente Teresa Lettini Caterina Foti Gennaro Cormio Eugenio Maiorano Leonardo Resta |
| author_sort | Gerardo Cazzato |
| collection | DOAJ |
| description | Background: balloon cell melanoma represents less than 1% of all histological forms of malignant melanoma and represents a diagnostic challenge for the dermatopathologist. Methods: in this paper we present our cases of BCM found in our daily practice from 1 January 2008 to 31 December 2021, and we conduct a review of the literature relating to this entity in the period from the first description, 1970, to early 2022. Results: four cases of melanoma balloon cell have been extrapolated from our electronic database, while in the review of the literature we have identified 115 cases of patients with primary and/or metastatic BCM. Conclusions: we believe that future studies with numerous case series are essential not only to increase the knowledge of the pathophysiology of this neoplasm but also to correctly evaluate the response of BCM patients to new oncological therapies. |
| first_indexed | 2024-03-10T00:01:15Z |
| format | Article |
| id | doaj.art-5d8c1c5c8bd34a049284192b0e372f10 |
| institution | Directory Open Access Journal |
| issn | 2296-3529 |
| language | English |
| last_indexed | 2024-03-10T00:01:15Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Dermatopathology |
| spelling | doaj.art-5d8c1c5c8bd34a049284192b0e372f102023-11-23T16:15:17ZengMDPI AGDermatopathology2296-35292022-03-019210011010.3390/dermatopathology9020013Balloon Cell Melanoma: Presentation of Four Cases with a Comprehensive Review of the LiteratureGerardo Cazzato0Eliano Cascardi1Anna Colagrande2Antonietta Cimmino3Giuseppe Ingravallo4Lucia Lospalluti5Paolo Romita6Aurora Demarco7Francesca Arezzo8Vera Loizzi9Miriam Dellino10Irma Trilli11Emilio Bellitti12Paola Parente13Teresa Lettini14Caterina Foti15Gennaro Cormio16Eugenio Maiorano17Leonardo Resta18Section of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Medical Sciences, University of Turin, 10121 Turin, ItalySection of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Dermatology, Department of Biomedical Science and Oncology (DIMO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Dermatology, Department of Biomedical Science and Oncology (DIMO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Dermatology, Department of Biomedical Science and Oncology (DIMO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Gynecology and Obstetrics, Department of Biomedical Sciences and Human Oncology (DIMO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Gynecology and Obstetrics, Department of Biomedical Sciences and Human Oncology (DIMO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Gynecology and Obstetrics, Department of Biomedical Sciences and Human Oncology (DIMO), University of Bari “Aldo Moro”, 70124 Bari, ItalyOdontomatostologic Clinic, Department of Innovative Technologies in Medicine and Dentistry, University of Chieti “G. D’Annunzio”, 66100 Chieti, ItalySection of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalyPathology Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, ItalySection of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Dermatology, Department of Biomedical Science and Oncology (DIMO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Gynecology and Obstetrics, Department of Biomedical Sciences and Human Oncology (DIMO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalyBackground: balloon cell melanoma represents less than 1% of all histological forms of malignant melanoma and represents a diagnostic challenge for the dermatopathologist. Methods: in this paper we present our cases of BCM found in our daily practice from 1 January 2008 to 31 December 2021, and we conduct a review of the literature relating to this entity in the period from the first description, 1970, to early 2022. Results: four cases of melanoma balloon cell have been extrapolated from our electronic database, while in the review of the literature we have identified 115 cases of patients with primary and/or metastatic BCM. Conclusions: we believe that future studies with numerous case series are essential not only to increase the knowledge of the pathophysiology of this neoplasm but also to correctly evaluate the response of BCM patients to new oncological therapies.https://www.mdpi.com/2296-3529/9/2/13malignant melanomaballoon celldifferential diagnosisdermatopathology |
| spellingShingle | Gerardo Cazzato Eliano Cascardi Anna Colagrande Antonietta Cimmino Giuseppe Ingravallo Lucia Lospalluti Paolo Romita Aurora Demarco Francesca Arezzo Vera Loizzi Miriam Dellino Irma Trilli Emilio Bellitti Paola Parente Teresa Lettini Caterina Foti Gennaro Cormio Eugenio Maiorano Leonardo Resta Balloon Cell Melanoma: Presentation of Four Cases with a Comprehensive Review of the Literature Dermatopathology malignant melanoma balloon cell differential diagnosis dermatopathology |
| title | Balloon Cell Melanoma: Presentation of Four Cases with a Comprehensive Review of the Literature |
| title_full | Balloon Cell Melanoma: Presentation of Four Cases with a Comprehensive Review of the Literature |
| title_fullStr | Balloon Cell Melanoma: Presentation of Four Cases with a Comprehensive Review of the Literature |
| title_full_unstemmed | Balloon Cell Melanoma: Presentation of Four Cases with a Comprehensive Review of the Literature |
| title_short | Balloon Cell Melanoma: Presentation of Four Cases with a Comprehensive Review of the Literature |
| title_sort | balloon cell melanoma presentation of four cases with a comprehensive review of the literature |
| topic | malignant melanoma balloon cell differential diagnosis dermatopathology |
| url | https://www.mdpi.com/2296-3529/9/2/13 |
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