Pancreatic Cancer Progression Is Regulated by IPO7/p53/LncRNA MALAT1/MiR-129-5p Positive Feedback Loop

Pancreatic Cancer Progression Is Regulated by IPO7/p53/LncRNA MALAT1/MiR-129-5p Positive Feedback Loop

Background: Pancreatic cancer is a malignancy with poor prognosis. Importin 7 (IPO7) is a soluble nuclear transport factor, which has been linked to the pathogenesis of several human diseases. However, its role and underlying mechanism in pancreatic cancer are still obscure.Methods: Immunohistochemi...

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Bibliographic Details
Main Authors: Jin Xu, Weixue Xu, Yang Xuan, Zhen Liu, Qinyun Sun, Cheng Lan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
IPO7
p53
MALAT1
miR-129-5p
pancreatic cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.630262/full

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