Type 1 Innate Lymphoid Cells Limit the Antitumoral Immune Response

Type 1 Innate Lymphoid Cells Limit the Antitumoral Immune Response

Natural killer (NK) cells are known to be able to kill established tumor cell lines, but important caveats remain regarding their roles in the detection and elimination of developing primary tumors. Using a genetic model of selective ILC1 and NK cell deficiency, we showed that these cells were dispe...

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Bibliographic Details
Main Authors: Margaux Vienne, Marion Etiennot, Bertrand Escalière, Justine Galluso, Lionel Spinelli, Sophie Guia, Aurore Fenis, Eric Vivier, Yann M. Kerdiles
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
innate
innate lymphoid cells (ILCs)
antitumoral immunity
NK cells
ILC1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.768989/full

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