Two adjacent and similar TetR family transcriptional regulator genes, SAV577 and SAV576, co-regulate avermectin production in Streptomyces avermitilis.

Streptomyces avermitilis is an important bacterial species used for industrial production of avermectins, a family of broad-spectrum anthelmintic agents. We previously identified the protein SAV576, a TetR family transcriptional regulator (TFR), as a downregulator of avermectin biosynthesis that act...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Jia Guo, Xuan Zhang, Zhi Chen, Ying Wen, Jilun Li
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Public Library of Science (PLoS) 2014-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0099224&type=printable