Two adjacent and similar TetR family transcriptional regulator genes, SAV577 and SAV576, co-regulate avermectin production in Streptomyces avermitilis.
Streptomyces avermitilis is an important bacterial species used for industrial production of avermectins, a family of broad-spectrum anthelmintic agents. We previously identified the protein SAV576, a TetR family transcriptional regulator (TFR), as a downregulator of avermectin biosynthesis that act...
Prif Awduron: | , , , , |
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Fformat: | Erthygl |
Iaith: | English |
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Public Library of Science (PLoS)
2014-01-01
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Cyfres: | PLoS ONE |
Mynediad Ar-lein: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0099224&type=printable |