Aqueous Extract of Cocoa Phenolic Compounds Protects Differentiated Neuroblastoma SH-SY5Y Cells from Oxidative Stress

Aqueous Extract of Cocoa Phenolic Compounds Protects Differentiated Neuroblastoma SH-SY5Y Cells from Oxidative Stress

Cocoa is a rich source of polyphenols, especially flavanols and procyanidin oligomers, with antioxidant properties, providing protection against oxidation and nitration. Cocoa phenolic compounds are usually extracted with methanol/ethanol solvents in order to obtain most of their bioactive compounds...

Full description

Bibliographic Details
Main Authors:	Noelia Carballeda Sangiao, Susana Chamorro, Sonia de Pascual-Teresa, Luis Goya
Format:	Article
Language:	English
Published:	MDPI AG 2021-08-01
Series:	Biomolecules
Subjects:	epicatechin neuronal-like cells reactive oxygen species glutathione antioxidant defenses
Online Access:	https://www.mdpi.com/2218-273X/11/9/1266

Similar Items

A Red-Berry Mixture as a Nutraceutical: Detailed Composition and Neuronal Protective Effect
by: Noelia Carballeda-Sangiao, et al.
Published: (2021-05-01)

Evaluation of the Anti-apoptotic and Anti-cytotoxic Effect of Epicatechin Gallate and Edaravone on SH-SY5Y Neuroblastoma Cells
by: Mohammad Shokrzadeh, et al.
Published: (2019-11-01)

Sucralose Targets the Insulin Signaling Pathway in the SH-SY5Y Neuroblastoma Cell Line
by: Marina Čović, et al.
Published: (2023-07-01)

Methylxanthine and catechin content of fresh and fermented cocoa beans, dried cocoa beans, and cocoa liquor
by: Pedro P. Peláez, et al.
Published: (2016-12-01)

Circulating Structurally Related (-)-Epicatechin Metabolite Species and Levels after Sustained Intake of a Cocoa Powder High in Polyphenols Are Comparable to Those Achieved after a Single Dose
by: Paloma K. Barrera-Reyes, et al.
Published: (2021-10-01)

The Kinetics of Total Phenolic Content and Monomeric Flavan-3-ols during the Roasting Process of Criollo Cocoa
by: Editha Fernández-Romero, et al.
Published: (2020-02-01)

Phenolic and Theobromine Contents of Commercial Dark, Milk and White Chocolates on the Malaysian Market
by: Cheng Chia Meng, et al.
Published: (2009-01-01)

Cocoa colonic phenolic metabolites are related to HDL-cholesterol raising effects and methylxanthine metabolites and insoluble dietary fibre to anti-inflammatory and hypoglycemic effects in humans
by: Beatriz Sarriá, et al.
Published: (2020-09-01)

Characterization of Polyphenols from Various Cocoa (Theobroma cacao L.) Clones During Fermentation
by: Muhammad Isa Dwijatmoko, et al.
Published: (2018-08-01)

Green tea and cocoa enhance cognition in Lymnaea
by: Erin Swinton, et al.
Published: (2018-01-01)

Cocoa and cocoa flavanol epicatechin improve hepatic lipid metabolism in in vivo and in vitro models. Role of PKCζ
by: Isabel Cordero-Herrera, et al.
Published: (2015-08-01)

Flavonoid Intake From Cocoa-Based Products and Adiposity Parameters in Adolescents in Spain
by: Emily P. Laveriano-Santos, et al.
Published: (2022-07-01)

Effect of 8-hydroxyquinoline and derivatives on human neuroblastoma SH-SY5Y cells under high glucose
by: Wilasinee Suwanjang, et al.
Published: (2016-08-01)

Neurocytotoxicity of imidacloprid- and acetamiprid-based comercial insecticides over the differentiation of SH-SY5Y neuroblastoma cells
by: Lenin J. Ramirez-Cando, et al.
Published: (2023-05-01)

Current update on the protective effect of epicatechin in neurodegenerative diseases
by: Riya Thapa, et al.
Published: (2022-06-01)

Upcycling flavanol‐rich Chardonnay and Pinot noir grape thinned clusters as potentially functional food ingredients in cocoa‐based products
by: Xueqi Li, et al.
Published: (2023-06-01)

Comparison of the Effects of Conching Parameters on the Contents of Three Dominant Flavan3-ols, Rheological Properties and Sensory Quality in Chocolate Milk Mass Based on Liquor from Unroasted Cocoa Beans
by: Bogumiła Urbańska, et al.
Published: (2021-04-01)

Lower nitrogen nutrition determines higher phenolic content of organic apples Juozas Lanauskas1, Darius Kviklys1, Mindaugas Liaudanskas2, Valdimaras
by: Juozas Lanauskas, et al.
Published: (2017-09-01)

Improvement of the Flavanol Profile and the Antioxidant Capacity of Chocolate Using a Phenolic Rich Cocoa Powder
by: Rocío González-Barrio, et al.
Published: (2020-02-01)

Membrane effects of Cocoa Procyanidins in Liposomes and Jurkat T Cells
by: SANDRA V. VERSTRAETEN, et al.
Published: (2004-01-01)

A Phenolic-rich Extract of Cocoa (Theobroma cacao L.) Beans Impairs the Pathogenic Properties of Porphyromonas gingivalis and Attenuates the Activation of Nuclear Factor Kappa B in a Monocyte Model
by: Katy Vaillancourt, et al.
Published: (2022-03-01)

Palmitic acid induces neurotoxicity and gliatoxicity in SH-SY5Y human neuroblastoma and T98G human glioblastoma cells
by: Yee-Wen Ng, et al.
Published: (2018-04-01)

Effects of HDAC inhibitors on neuroblastoma SH-SY5Y cell differentiation into mature neurons via the Wnt signaling pathway
by: Jiyun Choi, et al.
Published: (2023-05-01)

Improving Cardiovascular Risk in Postmenopausal Women with an (−)-Epicatechin-Based Nutraceutical: A Randomly Assigned, Double-Blind vs. Placebo, Proof-of-Concept Trial
by: Nayelli Nájera, et al.
Published: (2023-12-01)

Comparison of the methylglyoxal scavenging effects of kaempferol and glutathione and the consequences for the toxicity of methylglyoxal in SH-SY5Y cells
by: Liang Zheng, et al.
Published: (2023-12-01)

Cocoa polyphenols exhibit antioxidant, anti-inflammatory, anticancerogenic, and anti-necrotic activity in carbon tetrachloride-intoxicated mice
by: Jasminka Giacometti, et al.
Published: (2016-05-01)

Neuroprotective effects of Salvia aristata Aucher ex Benth. on hydrogen peroxide induced apoptosis in SH-SY5Y neuroblastoma cells
by: M. A. Esmaeili, et al.
Published: (2015-08-01)

Phenolic contents in fruit juices of plums with different skin colors
by: Katharina Goldner, et al.
Published: (2015-12-01)

The Effects of Green Tea Catechins in Hematological Malignancies
by: Fernanda Isabel Della Via, et al.
Published: (2023-07-01)

Metabolic Characterization of the Anthocyanidin Reductase Pathway Involved in the Biosynthesis of Flavan-3-ols in Elite Shuchazao Tea (Camellia sinensis) Cultivar in the Field
by: Lei Zhao, et al.
Published: (2017-12-01)

Antioxidant capacity, total phenolic content and phenolic compounds of pulp and bagasse of four Peruvian berries
by: Elizabeth Rojas-Ocampo, et al.
Published: (2021-08-01)

Phenolic compounds, methylxanthines and antioxidant activity in cocoa mass and chocolates produced from "witch broom disease" resistant and non resistant cocoa cultivars Compostos fenólicos, metilxantinas e atividade antioxidante em massa de cacau e chocolates produzidos a partir de cultivares resistentes e não resistentes a "vassoura de bruxa"
by: Paula Bacelar Leite, et al.
Published: (2013-06-01)

(−)-Epicatechin Inhibits Metastatic-Associated Proliferation, Migration, and Invasion of Murine Breast Cancer Cells In Vitro
by: Javier Pérez-Durán, et al.
Published: (2023-08-01)

Memantine, Simvastatin, and Epicatechin Inhibit 7-Ketocholesterol-induced Apoptosis in Retinal Pigment Epithelial Cells But Not Neurosensory Retinal Cells In Vitro
by: Aneesh Neekhra, et al.
Published: (2020-10-01)

Exploring the neuroprotective activity of a lignanamides-rich extract in human neuroblastoma SH-SY5Y cells under dimethyl sulfoxide-induced stress
by: Marta Mallardo, et al.
Published: (2024-03-01)

How Climatic Seasons of the Amazon Biome Affect the Aromatic and Bioactive Profiles of Fermented and Dried Cocoa Beans?
by: Daniela Pinheiro Gaspar, et al.
Published: (2021-06-01)

Increasing the TRPM2 Channel Expression in Human Neuroblastoma SH-SY5Y Cells Augments the Susceptibility to ROS-Induced Cell Death
by: Xinfang An, et al.
Published: (2019-01-01)

Effect of foliar treatment with chitosan on phenolic composition of ῾Fetească neagră’ grapes and wines
by: Victoria ARTEM, et al.
Published: (2023-02-01)

Retinoic Acid-Differentiated Neuroblastoma SH-SY5Y Is an Accessible In Vitro Model to Study Native Human Acid-Sensing Ion Channels 1a (ASIC1a)
by: Aleksandr P. Kalinovskii, et al.
Published: (2022-01-01)

On the cytotoxicity of HCR-NTPase in the neuroblastoma cell line SH-SY5Y
by: Pasdziernik Markus, et al.
Published: (2009-06-01)