On Complex Coacervate Core Micelles: Structure-Function Perspectives

The co-assembly of ionic-neutral block copolymers with oppositely charged species produces nanometric colloidal complexes, known, among other names, as complex coacervates core micelles (C3Ms). C3Ms are of widespread interest in nanomedicine for controlled delivery and release, whilst research activ...

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Main Authors: Jose Rodrigo Magana, Christian C. M. Sproncken, Ilja K. Voets
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/12/9/1953
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author Jose Rodrigo Magana
Christian C. M. Sproncken
Ilja K. Voets
author_facet Jose Rodrigo Magana
Christian C. M. Sproncken
Ilja K. Voets
author_sort Jose Rodrigo Magana
collection DOAJ
description The co-assembly of ionic-neutral block copolymers with oppositely charged species produces nanometric colloidal complexes, known, among other names, as complex coacervates core micelles (C3Ms). C3Ms are of widespread interest in nanomedicine for controlled delivery and release, whilst research activity into other application areas, such as gelation, catalysis, nanoparticle synthesis, and sensing, is increasing. In this review, we discuss recent studies on the functional roles that C3Ms can fulfil in these and other fields, focusing on emerging structure–function relations and remaining knowledge gaps.
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spelling doaj.art-5d9bd545cbe74bef99cd76670d2dc59a2023-11-20T11:45:35ZengMDPI AGPolymers2073-43602020-08-01129195310.3390/polym12091953On Complex Coacervate Core Micelles: Structure-Function PerspectivesJose Rodrigo Magana0Christian C. M. Sproncken1Ilja K. Voets2Laboratory of Self-Organizing Soft Matter, Department of Chemical Engineering and Chemistry and Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The NetherlandsLaboratory of Self-Organizing Soft Matter, Department of Chemical Engineering and Chemistry and Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The NetherlandsLaboratory of Self-Organizing Soft Matter, Department of Chemical Engineering and Chemistry and Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The NetherlandsThe co-assembly of ionic-neutral block copolymers with oppositely charged species produces nanometric colloidal complexes, known, among other names, as complex coacervates core micelles (C3Ms). C3Ms are of widespread interest in nanomedicine for controlled delivery and release, whilst research activity into other application areas, such as gelation, catalysis, nanoparticle synthesis, and sensing, is increasing. In this review, we discuss recent studies on the functional roles that C3Ms can fulfil in these and other fields, focusing on emerging structure–function relations and remaining knowledge gaps.https://www.mdpi.com/2073-4360/12/9/1953co-assemblycomplex coacervate core micelleinterpolyelectrolyte complexpolyelectrolytespolyion complexpolyplex
spellingShingle Jose Rodrigo Magana
Christian C. M. Sproncken
Ilja K. Voets
On Complex Coacervate Core Micelles: Structure-Function Perspectives
Polymers
co-assembly
complex coacervate core micelle
interpolyelectrolyte complex
polyelectrolytes
polyion complex
polyplex
title On Complex Coacervate Core Micelles: Structure-Function Perspectives
title_full On Complex Coacervate Core Micelles: Structure-Function Perspectives
title_fullStr On Complex Coacervate Core Micelles: Structure-Function Perspectives
title_full_unstemmed On Complex Coacervate Core Micelles: Structure-Function Perspectives
title_short On Complex Coacervate Core Micelles: Structure-Function Perspectives
title_sort on complex coacervate core micelles structure function perspectives
topic co-assembly
complex coacervate core micelle
interpolyelectrolyte complex
polyelectrolytes
polyion complex
polyplex
url https://www.mdpi.com/2073-4360/12/9/1953
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