Multiple primary malignant neoplasms of the mouth and oropharynx
Introduction. Probability of development of multiple primary tumors in patients who received treatment due to head and neck cancers varies between 5.6 and 35.9 % per different sources. moreover, treatment capabilities are severely limited by postoperative anatomical changes and previous radiation th...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2022-08-01
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| Series: | Опухоли головы и шеи |
| Subjects: | |
| Online Access: | https://ogsh.abvpress.ru/jour/article/view/777 |
| _version_ | 1797876146475368448 |
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| author | M. A. Kropotov L. P. Yakovleva L. G. Zhukova G. O. Agabekyan A. V. Khodos D. A. Safarov P. A. Gavrishchuk M. S. Tigrov A. S. Vyalov |
| author_facet | M. A. Kropotov L. P. Yakovleva L. G. Zhukova G. O. Agabekyan A. V. Khodos D. A. Safarov P. A. Gavrishchuk M. S. Tigrov A. S. Vyalov |
| author_sort | M. A. Kropotov |
| collection | DOAJ |
| description | Introduction. Probability of development of multiple primary tumors in patients who received treatment due to head and neck cancers varies between 5.6 and 35.9 % per different sources. moreover, treatment capabilities are severely limited by postoperative anatomical changes and previous radiation therapy, and the second tumor frequently causes death in these patients.The study objective is to identify the epidemiological features of the development of synchronous and metachronous primary multiple tumors in the head and neck.Materials and methods. The article analyzes data on 103 patients with multiple primary tumors who received treatment due to tumors of the head and neck between 1991 and 2020 at the N.N. Blokhin National medical Research Center of Oncology and A.S. Loginov Moscow Clinical Scientific Center.Results. During the study, typical locations of metachronous tumors in patients who received treatment due to primary malignant tumors of the head and neck were determined, duration of development of multiple primary tumors, treatment methods and survival rates were analyzed.Conclusion. Due to high risk of multiple primary tumors in patients who received treatment due to malignant tumors of the head and neck in the next 5 plus years, it is expedient to observe these patients during their whole lifetime. Considering typical locations of metachronous tumors, examination during dynamic observation should include instrumental methods such as panendoscopy. Surgical treatment should involve the whole spectrum of minimally invasive interventions including CO2 laser surgery and transoral robot-assisted interventions. |
| first_indexed | 2024-04-10T01:58:34Z |
| format | Article |
| id | doaj.art-5d9c2d503a4b447e80a39d2b46c50be0 |
| institution | Directory Open Access Journal |
| issn | 2222-1468 2411-4634 |
| language | Russian |
| last_indexed | 2024-04-10T01:58:34Z |
| publishDate | 2022-08-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли головы и шеи |
| spelling | doaj.art-5d9c2d503a4b447e80a39d2b46c50be02023-03-13T08:43:22ZrusABV-pressОпухоли головы и шеи2222-14682411-46342022-08-01122556210.17650/2222-1468-2022-12-2-55-62497Multiple primary malignant neoplasms of the mouth and oropharynxM. A. Kropotov0L. P. Yakovleva1L. G. Zhukova2G. O. Agabekyan3A. V. Khodos4D. A. Safarov5P. A. Gavrishchuk6M. S. Tigrov7A. S. Vyalov8Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина Минздрава РоссииМосковский клинический научный центр им. А.С. Логинова Департамента здравоохранения г. МосквыМосковский клинический научный центр им. А.С. Логинова Департамента здравоохранения г. МосквыНациональный медицинский исследовательский центр нейрохирургии им. акад. Н.Н. Бурденко Минздрава РоссииМосковский клинический научный центр им. А.С. Логинова Департамента здравоохранения г. МосквыНациональный медицинский исследовательский центр онкологии им. Н.Н. Блохина Минздрава РоссииМосковский клинический научный центр им. А.С. Логинова Департамента здравоохранения г. МосквыМосковский клинический научный центр им. А.С. Логинова Департамента здравоохранения г. МосквыМосковский клинический научный центр им. А.С. Логинова Департамента здравоохранения г. МосквыIntroduction. Probability of development of multiple primary tumors in patients who received treatment due to head and neck cancers varies between 5.6 and 35.9 % per different sources. moreover, treatment capabilities are severely limited by postoperative anatomical changes and previous radiation therapy, and the second tumor frequently causes death in these patients.The study objective is to identify the epidemiological features of the development of synchronous and metachronous primary multiple tumors in the head and neck.Materials and methods. The article analyzes data on 103 patients with multiple primary tumors who received treatment due to tumors of the head and neck between 1991 and 2020 at the N.N. Blokhin National medical Research Center of Oncology and A.S. Loginov Moscow Clinical Scientific Center.Results. During the study, typical locations of metachronous tumors in patients who received treatment due to primary malignant tumors of the head and neck were determined, duration of development of multiple primary tumors, treatment methods and survival rates were analyzed.Conclusion. Due to high risk of multiple primary tumors in patients who received treatment due to malignant tumors of the head and neck in the next 5 plus years, it is expedient to observe these patients during their whole lifetime. Considering typical locations of metachronous tumors, examination during dynamic observation should include instrumental methods such as panendoscopy. Surgical treatment should involve the whole spectrum of minimally invasive interventions including CO2 laser surgery and transoral robot-assisted interventions.https://ogsh.abvpress.ru/jour/article/view/777плоскоклеточный ракопухоли головы и шеипервично-множественные опухолиреконструктивная хирургиясo<sub>2</sub>-лазерная хирургиятрансоральная хирургия |
| spellingShingle | M. A. Kropotov L. P. Yakovleva L. G. Zhukova G. O. Agabekyan A. V. Khodos D. A. Safarov P. A. Gavrishchuk M. S. Tigrov A. S. Vyalov Multiple primary malignant neoplasms of the mouth and oropharynx Опухоли головы и шеи плоскоклеточный рак опухоли головы и шеи первично-множественные опухоли реконструктивная хирургия сo<sub>2</sub>-лазерная хирургия трансоральная хирургия |
| title | Multiple primary malignant neoplasms of the mouth and oropharynx |
| title_full | Multiple primary malignant neoplasms of the mouth and oropharynx |
| title_fullStr | Multiple primary malignant neoplasms of the mouth and oropharynx |
| title_full_unstemmed | Multiple primary malignant neoplasms of the mouth and oropharynx |
| title_short | Multiple primary malignant neoplasms of the mouth and oropharynx |
| title_sort | multiple primary malignant neoplasms of the mouth and oropharynx |
| topic | плоскоклеточный рак опухоли головы и шеи первично-множественные опухоли реконструктивная хирургия сo<sub>2</sub>-лазерная хирургия трансоральная хирургия |
| url | https://ogsh.abvpress.ru/jour/article/view/777 |
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